Immunology of age-related macular degeneration

J Ambati, JP Atkinson, BD Gelfand - Nature Reviews Immunology, 2013 - nature.com
Age-related macular degeneration (AMD) is a leading cause of blindness in aged
individuals. Recent advances have highlighted the essential role of immune processes in …

Geographic atrophy: clinical features and potential therapeutic approaches

FG Holz, EC Strauss, S Schmitz-Valckenberg… - Ophthalmology, 2014 - Elsevier
In contrast to wet age-related macular degeneration (AMD), where loss of vision is typically
acute and treatment leads to a relatively rapid reduction in retinal fluid and subsequent …

Risk of geographic atrophy in the comparison of age-related macular degeneration treatments trials

JE Grunwald, E Daniel, J Huang, G Ying, MG Maguire… - Ophthalmology, 2014 - Elsevier
Purpose To describe risk factors for geographic atrophy (GA) in the Comparison of Age-
related Macular Degeneration Treatments Trials (CATT). Design Cohort within a randomized …

[HTML][HTML] A new perspective on lipid research in age-related macular degeneration

EM van Leeuwen, E Emri, BMJ Merle, JM Colijn… - Progress in retinal and …, 2018 - Elsevier
There is an urgency to find new treatment strategies that could prevent or delay the onset or
progression of AMD. Different classes of lipids and lipoproteins metabolism genes have …

Age-related macular degeneration

EK de Jong, MJ Geerlings, AI den Hollander - Genetics and genomics of …, 2020 - Elsevier
Age-related macular degeneration (AMD) is a multifactorial disease influenced by a
combination of environmental factors and genetic variants. Genomic studies have been …

Age-related macular degeneration revisited–piecing the puzzle: the LXIX Edward Jackson memorial lecture

JW Miller - American journal of ophthalmology, 2013 - Elsevier
PURPOSE: To present the current understanding of age-related macular degeneration
(AMD) pathogenesis, based on clinical evidence, epidemiologic data, histopathologic …

Pachychoroid neovasculopathy and age-related macular degeneration

M Miyake, S Ooto, K Yamashiro, A Takahashi… - Scientific reports, 2015 - nature.com
Pachychoroid neovasculopathy is a recently proposed clinical entity of choroidal
neovascularization (CNV). As it often masquerades as neovascular age-related macular …

Nature and nurture-genes and environment-predict onset and progression of macular degeneration

L Sobrin, JM Seddon - Progress in retinal and eye research, 2014 - Elsevier
Age-related macular degeneration (AMD) is a common cause of irreversible visual loss and
the disease burden is rising world-wide as the population ages. Both environmental and …

[HTML][HTML] Optical coherence tomography features preceding the onset of advanced age-related macular degeneration

D Ferrara, RE Silver, RN Louzada… - … & visual science, 2017 - tvst.arvojournals.org
Purpose: Age-related macular degeneration (AMD) is a progressive disease with
multifactorial etiology. There is a need to identify clinical features that are harbingers of …

[HTML][HTML] Adaptive optics technology for high-resolution retinal imaging

M Lombardo, S Serrao, N Devaney, M Parravano… - Sensors, 2013 - mdpi.com
Adaptive optics (AO) is a technology used to improve the performance of optical systems by
reducing the effects of optical aberrations. The direct visualization of the photoreceptor cells …