Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …

Interstitial lung disease (ILD) is one of the most serious pulmonary complications associated
with connective tissue diseases (CTDs), resulting in significant morbidity and mortality …

Within the spectrum of fibrosing interstitial lung diseases (ILDs) is a subset of patients who
have inexorable progression of pulmonary fibrosis despite treatment, which is known as the …

Objectives To identify overall disease course, progression patterns and risk factors
predictive for progressive interstitial lung disease (ILD) in patients with systemic sclerosis …

Rationale: Gastroesophageal reflux (GER) is highly prevalent in patients with idiopathic
pulmonary fibrosis (IPF). Chronic microaspiration secondary to GER may play a role in the …

Background Gastroesophageal reflux disease (GERD) is one of the most frequent benign
disorders of the upper gastrointestinal tract. Management of GERD has always been …

Systemic sclerosis (SSc) is a systemic autoimmune disease that is characterised by
endothelial dysfunction resulting in a small-vessel vasculopathy, fibroblast dysfunction with …

Approximately a third of patients with suspected gastro-oesophageal reflux disease are
resistant or partial responders to proton pump inhibitors (PPIs). Many of these patients do …

Systemic sclerosis (SSc) is a multisystem autoimmune and vascular disease resulting in
fibrosis of various organs with unknown etiology. Accumulating evidence suggests that a …

Systemic sclerosis (SSc) is a rare autoimmune disease characterized by fibroproliferative
alterations of the microvasculature leading to fibrosis and loss of function of the skin and …