Recent Advances in the Use of Galleria mellonella Model to Study Immune Responses against Human Pathogens

TC Pereira, PP De Barros, LRO Fugisaki, RD Rossoni… - Journal of Fungi, 2018 - mdpi.com
The use of invertebrates for in vivo studies in microbiology is well established in the scientific
community. Larvae of Galleria mellonella are a widely used model for studying …

Pathogenicity patterns of mucormycosis: epidemiology, interaction with immune cells and virulence factors

MIA Hassan, K Voigt - Medical Mycology, 2019 - academic.oup.com
Fungi of the basal lineage order Mucorales are able to cause infections in animals and
humans. Mucormycosis is a well-known, life-threatening disease especially in patients with …

The Virtuous Galleria mellonella Model for Scientific Experimentation

I Serrano, C Verdial, L Tavares, M Oliveira - Antibiotics, 2023 - mdpi.com
The first research on the insect Galleria mellonella was published 85 years ago, and the
larva is now widely used as a model to study infections caused by bacterial and fungal …

The silkworm (Bombyx mori) gut microbiota is involved in metabolic detoxification by glucosylation of plant toxins

S Yuan, Y Sun, W Chang, J Zhang, J Sang… - Communications …, 2023 - nature.com
Herbivores have evolved the ability to detoxify feed components through different
mechanisms. The oligophagous silkworm feeds on Cudrania tricuspidata leaves (CTLs) …

Aspergillus fumigatus and aspergillosis: From basics to clinics

A Arastehfar, A Carvalho, J Houbraken… - Studies in …, 2021 - ingentaconnect.com
The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …

Mucormycosis in 2023: An update on pathogenesis and management

A Alqarihi, DP Kontoyiannis, AS Ibrahim - Frontiers in Cellular and …, 2023 - frontiersin.org
Mucormycosis (MCR) is an emerging and frequently lethal fungal infection caused by the
Mucorales family, with Rhizopus, Mucor, and Lichtheimia, accounting for> 90% of all cases …

Galleria mellonella for the Evaluation of Antifungal Efficacy against Medically Important Fungi, a Narrative Review

S Jemel, J Guillot, K Kallel, F Botterel, E Dannaoui - Microorganisms, 2020 - mdpi.com
The treatment of invasive fungal infections remains challenging and the emergence of new
fungal pathogens as well as the development of resistance to the main antifungal drugs …

The Use of Galleria mellonella Larvae to Identify Novel Antimicrobial Agents against Fungal Species of Medical Interest

K Kavanagh, G Sheehan - Journal of Fungi, 2018 - mdpi.com
The immune system of insects and the innate immune response of mammals share many
similarities and, as a result, insects may be used to assess the virulence of fungal pathogens …

[PDF][PDF] de Paula e Silva

L Scorzoni - 2004 - pdfs.semanticscholar.org
Background: Paracoccidioidomycosis (PCM) is a chronic disease that causes sequelae and
requires prolonged treatment; therefore, new therapeutic approaches are necessary. In view …

Rearing and Maintenance of Galleria mellonella and Its Application to Study Fungal Virulence

C Firacative, A Khan, S Duan, K Ferreira-Paim… - Journal of Fungi, 2020 - mdpi.com
Galleria mellonella larvae have been widely used as alternative non-mammalian models for
the study of fungal virulence and pathogenesis. The larvae can be acquired in small …