Vascular endothelial cells form the inner layer of blood vessels where they have a key role
in the development and maintenance of the functional circulatory system and provide …

Single-cell sequencing technologies, including transcriptomic and epigenomic assays, are
transforming our understanding of the cellular building blocks of neural circuits. By directly …

For more than 100 years, the fruit fly Drosophila melanogaster has been one of the most
studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula …

A mammalian brain is composed of numerous cell types organized in an intricate manner to
form functional neural circuits. Single-cell RNA sequencing allows systematic identification …

Dendritic and axonal morphology reflects the input and output of neurons and is a defining
feature of neuronal types,, yet our knowledge of its diversity remains limited. Here, to …

The mesenchymal subtype of glioblastoma is thought to be determined by both cancer cell-
intrinsic alterations and extrinsic cellular interactions, but remains poorly understood. Here …

Here we present a compendium of single-cell transcriptomic data from the model organism
Mus musculus that comprises more than 100,000 cells from 20 organs and tissues. These …

We have created a compendium of single cell transcriptomic data from the model organism
Mus musculus comprising more than 100,000 cells from 20 organs and tissues. These data …

INTRODUCTION A mechanistic understanding of brain function requires the identification of
distinct cell types in the brain at a molecular, spatial, and functional level. The preoptic …

The mammalian nervous system executes complex behaviors controlled by specialized,
precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a …