The increasing prevalence of multidrug-resistant bacterial infections necessitates the
exploration of novel paradigms for anti-infective therapy. Antimicrobial peptides (AMPs), also …

Covering: 2010 to 2022 Heterologous expression of natural product biosynthetic gene
clusters (BGCs) has become a widely used tool for genome mining of cryptic pathways …

The increasing market demands of β‐carotene as colorant, antioxidant and vitamin
precursor, requires novel biotechnological production platforms. Yarrowia lipolytica, is an …

Control of the lac operon with isopropyl β-d-1-thiogalactopyranoside (IPTG) has been used
to regulate gene expression in Escherichia coli for countless applications, including …

Natural products from fungi represent an important source of biologically active metabolites
notably for therapeutic agent development. Genome sequencing revealed that the number …

Here, we report the design, construction, and characterization of a tRNA neochromosome, a
designer chromosome that functions as an additional, de novo counterpart to the native …

Covering: 2000 to 2018, particularly from 2010 to early 2018 The increase in the incidence
of antibiotic resistant infections is threatening to overwhelm healthcare practices worldwide …

Since the onset of microbiology in the late 19th century, scientists have been growing
microorganisms almost exclusively as pure cultures, resulting in a limited and biased view of …

Synthetic biology tools, such as modular parts and combinatorial DNA assembly, are
routinely used to optimise the productivity of heterologous metabolic pathways for …

Living materials, which are composites of living cells residing in a polymeric matrix, are
designed to utilize the innate functionalities of the cells to address a broad range of …