Osteoarthritis: pathology, diagnosis, and treatment options

B Abramoff, FE Caldera - Medical Clinics, 2020 - medical.theclinics.com
Osteoarthritis (OA) is endemic throughout the world. An estimated 30.8 million adults in the
United States and 300 million individuals worldwide are living with OA. 1, 2 It is the leading …

[HTML][HTML] Silk fibroin-based biomaterials for cartilage/osteochondral repair

Z Zhou, J Cui, S Wu, Z Geng, J Su - Theranostics, 2022 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a common joint disease with a high disability rate. In addition, OA not
only causes great physiological and psychological harm to patients, but also puts great …

A systematic review of the incidence, prevalence, costs, and activity and work limitations of amputation, osteoarthritis, rheumatoid arthritis, back pain, multiple sclerosis …

J Lo, L Chan, S Flynn - Archives of physical medicine and rehabilitation, 2021 - Elsevier
Objectives To present recent evidence on the prevalence, incidence, costs, activity
limitations, and work limitations of common conditions requiring rehabilitation. Data Sources …

[HTML][HTML] Prevalence of arthritis and arthritis-attributable activity limitation—United States, 2016–2018

KA Theis - MMWR. Morbidity and mortality weekly report, 2021 - cdc.gov
Prevalence of Arthritis and Arthritis-Attributable Activity Limitation — United States, 2016–2018 |
MMWR Skip directly to site content Skip directly to page options Skip directly to AZ link Centers …

Culture-expanded mesenchymal stromal cell therapy: does it work in knee osteoarthritis? A pathway to clinical success

G Copp, KP Robb, S Viswanathan - Cellular & Molecular Immunology, 2023 - nature.com
Osteoarthritis (OA) is a degenerative multifactorial disease with concomitant structural,
inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific …

A molecular quantitative trait locus map for osteoarthritis

J Steinberg, L Southam, TI Roumeliotis… - Nature …, 2021 - nature.com
Osteoarthritis causes pain and functional disability for over 500 million people worldwide. To
develop disease-stratifying tools and modifying therapies, we need a better understanding …

Deep learning predicts total knee replacement from magnetic resonance images

AA Tolpadi, JJ Lee, V Pedoia, S Majumdar - Scientific reports, 2020 - nature.com
Knee Osteoarthritis (OA) is a common musculoskeletal disorder in the United States. When
diagnosed at early stages, lifestyle interventions such as exercise and weight loss can slow …

S100 proteins in rheumatic diseases

J Austermann, C Spiekermann, J Roth - Nature Reviews Rheumatology, 2018 - nature.com
Rheumatic diseases are characterized by sterile inflammation that causes severe long-term
damage to various organ systems. A growing body of evidence supports a pivotal role for the …

Cost utility analysis of dupilumab versus endoscopic sinus surgery for chronic rhinosinusitis with nasal polyps

GA Scangas, AW Wu, JY Ting, R Metson… - The …, 2021 - Wiley Online Library
Objective Both endoscopic sinus surgery (ESS) and biologic therapies have shown
effectiveness for medically‐refractory chronic rhinosinusitis with nasal polyps (CRSwNP) …

Hydrazone covalent adaptable networks modulate extracellular matrix deposition for cartilage tissue engineering

BM Richardson, DG Wilcox, MA Randolph, KS Anseth - Acta biomaterialia, 2019 - Elsevier
Cartilage tissue engineering strategies often rely on hydrogels with fixed covalent crosslinks
for chondrocyte encapsulation, yet the resulting material properties are largely elastic and …