The advent of direct-acting antivirals (DAAs) has transformed the treatment landscape of hepatitis C. To date, over 95% of the hepatitis C virus (HCV)-infected patients who received …
CD Ma, M Imamura, DC Talley, A Rolt, X Xu… - Nature …, 2020 - nature.com
Fluoxazolevir is an aryloxazole-based entry inhibitor of hepatitis C virus (HCV). We show that fluoxazolevir inhibits fusion of HCV with hepatic cells by binding HCV envelope protein …
M Kjellin, H Kileng, D Akaberi… - Scandinavian journal …, 2019 - Taylor & Francis
Abstract Background: The NS5A resistance-associated substitution (RAS) Y93H is found quite frequently (5–10%) at baseline in direct-acting antiviral agents (DAA) treatment-naïve …
M Merli, R Rossotti, G Travi, F Ferla… - Transplant Infectious …, 2019 - Wiley Online Library
Direct‐acting antivirals (DAAs) demonstrated high efficacy and safety even in the post‐liver transplant (LT) setting and in HIV‐infected patients, but data are very limited in the early post …
Chronic hepatitis C: Epidemiology, viral resistance, and public health implications Chronic hepatitis C virus (HCV) infection can progress to cirrhosis and end-stage liver disease. The …
The advent of direct-acting antivirals (DAAs) has transformed the treatment landscape of hepatitis C. To date, over 95% of the hepatitis C virus (HCV)-infected patients who received …