Exploiting endocytosis for non-spherical nanoparticle cellular uptake

S Niaz, B Forbes, BT Raimi-Abraham - Nanomanufacturing, 2022 - mdpi.com
Several challenges exist for successful nanoparticle cellular uptake—they must be able to
cross many physical barriers to reach their target and overcome the cell membrane. A …

Endocytic pathways of pathogenic protein aggregates in neurodegenerative diseases

P Hivare, K Mujmer, G Swarup, S Gupta, D Bhatia - Traffic, 2023 - Wiley Online Library
Endocytosis is the fundamental uptake process through which cells internalize extracellular
materials and species. Neurodegenerative diseases (NDs) are characterized by a …

Cryo-EM of the dynamin polymer assembled on lipid membrane

L Kong, KA Sochacki, H Wang, S Fang, B Canagarajah… - Nature, 2018 - nature.com
Membrane fission is a fundamental process in the regulation and remodelling of cell
membranes. Dynamin, a large GTPase, mediates membrane fission by assembling around …

Macrophage-engineered vesicles for therapeutic delivery and bidirectional reprogramming of immune cell polarization

KR Neupane, JR McCorkle, TJ Kopper, JE Lakes… - ACS …, 2021 - ACS Publications
Macrophages, one of the most important phagocytic cells of the immune system, are highly
plastic and are known to exhibit diverse roles under different pathological conditions. The …

Dynamin A as a one-component division machinery for synthetic cells

N De Franceschi, R Barth, S Meindlhumer… - Nature …, 2024 - nature.com
Membrane abscission, the final cut of the last connection between emerging daughter cells,
is an indispensable event in the last stage of cell division and in other cellular processes …

[HTML][HTML] The advantage of channeling nucleotides for very processive functions

D Zala, U Schlattner, T Desvignes, J Bobe… - …, 2017 - ncbi.nlm.nih.gov
Nucleoside triphosphate (NTP) s, like ATP (adenosine 5'-triphosphate) and GTP (guanosine
5'-triphosphate), have long been considered sufficiently concentrated and diffusible to fuel …

A DNM2 centronuclear myopathy mutation reveals a link between recycling endosome scission and autophagy

C Puri, MM Manni, M Vicinanza, C Hilcenko, Y Zhu… - Developmental cell, 2020 - cell.com
Autophagy involves engulfment of cytoplasmic contents by double-membraned
autophagosomes, which ultimately fuse with lysosomes to enable degradation of their …

The C-type lectin langerin functions as a receptor for attachment and infectious entry of influenza A virus

WC Ng, SL Londrigan, N Nasr, AL Cunningham… - Journal of …, 2016 - Am Soc Microbiol
It is well established that influenza A virus (IAV) attachment to and infection of epithelial cells
is dependent on sialic acid (SIA) at the cell surface, although the specific receptors that …

Resistance to white spot syndrome virus in the European shore crab is associated with suppressed virion trafficking and heightened immune responses

RS Millard, LK Bickley, KS Bateman… - Frontiers in …, 2022 - frontiersin.org
Introduction All decapod crustaceans are considered potentially susceptible to White Spot
Syndrome Virus (WSSV) infection, but the degree of White Spot Disease (WSD) …

[HTML][HTML] Intersectin scaffold proteins and their role in cell signaling and endocytosis

E Herrero-Garcia, JP O'Bryan - … et Biophysica Acta (BBA)-Molecular Cell …, 2017 - Elsevier
Intersectins (ITSNs) are a family of multi-domain proteins involved in regulation of diverse
cellular pathways. These scaffold proteins are well known for regulating endocytosis but …