MicroRNAs (miRNAs) play indispensable roles in posttranscriptional gene regulation. Their
cellular regulatory impact is determined not solely by their sheer number, which likely …

RNA therapeutics have emerged as next-generation therapy for the treatment of many
diseases. Unlike small molecules, RNA targeted drugs are not limited by the availability of …

Non-coding RNAs (ncRNAs), notably microRNAs (miRNAs) and long noncoding RNAs
(lncRNAs), have recently gained increasing consideration because of their versatile role as …

As an inherited disorder characterized by severe pulmonary disease, cystic fibrosis could be
considered a comorbidity for coronavirus disease 2019. Instead, current clinical evidence …

The unique properties of peptide nucleic acid (PNA) makes it a desirable candidate to be
used in therapeutic and biotechnological interventions. It has been broadly utilized for …

The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene encodes for a
chloride channel defective in Cystic Fibrosis (CF). Accordingly, upregulation of its …

Cystic fibrosis (CF) is a lifelong disorder affecting 1 in 3500 live births worldwide. It is a
monogenetic autosomal recessive disease caused by loss-of-function mutations in the gene …

Peptide nucleic acid (PNA) is a DNA analog, in which the sugar-phosphate backbone in
DNA is replaced by poly [N-(2-aminoethyl) glycine]. Since its discovery in the early 1990s …

Cystic fibrosis (CF) is an autosomal recessive disease which involves the mutations in the
cystic fibrosis transmembrane conductance regulator (CFTR) gene. CF involves in the …

Cystic fibrosis (CF) is an autosomal recessive disease impacting∼ 100,000 people
worldwide. This lethal disorder is caused by mutation of the CF transmembrane …