Alzheimer's disease (AD) is a genetically complex and heterogeneous disorder with
multifaceted neuropathological features, including β-amyloid plaques, neurofibrillary …

IL-17 cytokine family members have diverse biological functions, promoting protective
immunity against many pathogens but also driving inflammatory pathology during infection …

Cytokines are key messengers by which immune cells communicate, and they drive many
physiological processes, including immune and inflammatory responses. Early discoveries …

Hypertension (HTN), a disease afflicting over one billion individuals worldwide, is a leading
cause of cognitive impairment, the mechanisms of which remain poorly understood. In the …

Abstract In mammals, interleukin (IL)-17 cytokines are produced by innate and adaptive
lymphocytes. However, the IL-17 family has widespread expression throughout evolution …

APOE4 is the strongest genetic risk factor for Alzheimer's disease (AD), with increased odds
ratios in female carriers. Targeting amyloid plaques shows modest improvement in male non …

Ginseng has been used in China as a superior medicinal material for thousands of years
that can nourish the five internal organs, calm the mind and benefit wisdom. Due to its anti …

Neurological disorders (NDs) are one of the leading causes of global death. A sustained
neuroinflammatory response has been reported to be associated with the pathogenesis of …

T cells, the critical immune cells of the adaptive immune system, are often dysfunctional in
Alzheimer's disease (AD) and are involved in AD pathology. Reports highlight …

Unconventional T cells include γδ T cells, invariant Natural Killer T cells (iNKT) cells and
Mucosal Associated Invariant T (MAIT) cells, which are distinguished from conventional T …