The cuprizone animal model: new insights into an old story

M Kipp, T Clarner, J Dang, S Copray, C Beyer - Acta neuropathologica, 2009 - Springer
Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease that affects the
central nervous system and represents the most common neurological disorder in young …

Bioluminescence imaging: progress and applications

CE Badr, BA Tannous - Trends in biotechnology, 2011 - cell.com
Application of bioluminescence imaging has increased tremendously in the past decade
and has significantly contributed to core conceptual advances in biomedical research. This …

Differentiation of induced pluripotent stem cells into functional oligodendrocytes

M Czepiel, V Balasubramaniyan, W Schaafsma… - Glia, 2011 - Wiley Online Library
The technology to generate autologous pluripotent stem cells (iPS cells) from almost any
somatic cell type has brought various cell replacement therapies within clinical research …

Long‐term MR cell tracking of neural stem cells grafted in immunocompetent versus immunodeficient mice reveals distinct differences in contrast between live and …

SC Berman, C Galpoththawela, AA Gilad… - Magnetic resonance …, 2011 - Wiley Online Library
Neural stem cell (NSC)‐based therapy is actively being pursued in preclinical and clinical
disease models. Magnetic resonance imaging (MRI) cell tracking promises to optimize …

Comparative study of methods for administering neural stem/progenitor cells to treat spinal cord injury in mice

Y Takahashi, O Tsuji, G Kumagai, CM Hara… - Cell …, 2011 - journals.sagepub.com
To investigate potential cures for spinal cord injury (SCI), several researchers have
transplanted neural stem/progenitor cells (NS/PCs) into the injured spinal cord by different …

Current challenges for the advancement of neural stem cell biology and transplantation research

K Reekmans, J Praet, J Daans, V Reumers… - Stem cell reviews and …, 2012 - Springer
Transplantation of neural stem cells (NSC) is hoped to become a promising primary or
secondary therapy for the treatment of various neurodegenerative disorders of the central …

Boosting bioluminescence neuroimaging: an optimized protocol for brain studies

M Aswendt, J Adamczak, S Couillard-Despres… - PloS one, 2013 - journals.plos.org
Bioluminescence imaging is widely used for optical cell tracking approaches. However,
reliable and quantitative bioluminescence of transplanted cells in the brain is highly …

Human embryonic stem cell-derived oligodendrocyte progenitors aid in functional recovery of sensory pathways following contusive spinal cord injury

AH All, FA Bazley, S Gupta, N Pashai, C Hu… - 2012 - journals.plos.org
Background Transplantations of human stem cell derivatives have been widely investigated
in rodent models for the potential restoration of function of neural pathways after spinal cord …

Quantitative in vivo dual-color bioluminescence imaging in the mouse brain

M Aswendt, S Vogel, C Schäfer, A Jathoul… - …, 2019 - spiedigitallibrary.org
Bioluminescence imaging (BLI) is an optical imaging method that can be translated from the
cell culture dish in vitro to cell tracking in small animal models in vivo. In contrast to the more …

Evaluating reporter genes of different luciferases for optimized in vivo bioluminescence imaging of transplanted neural stem cells in the brain

L Mezzanotte, M Aswendt, A Tennstaedt… - Contrast media & …, 2013 - Wiley Online Library
Bioluminescence imaging (BLI) has become the method of choice for optical tracking of cells
in small laboratory animals. However, the use of luciferases from different species …