A continuous-flow electrochemical synthesis platform has been developed to enable self-
optimization of reaction conditions of organic electrochemical reactions using attenuated …

Chemometric methods are broadly used in the chemical and biochemical sectors. Typically,
derivation of a regression model follows data preprocessing in a sequential manner. Yet …

Kinetic parameter estimation from in situ spectroscopic data, such as those from infrared or
Raman spectroscopy, remains a challenging and highly active research area. Obtaining …

A methodology is proposed to aid parameter estimation in fundamental models of
pharmaceutical processes. This methodology addresses situations with insufficient data to …

Laboratory and process measurements from spectroscopic instruments are ubiquitous in
pharma processes, and directly using the data can pose a number of challenges for kinetic …

Multivariate spectroscopic data is increasingly abundant in the chemical and pharmaceutical
industries. However, it is often challenging to estimate reaction kinetics directly from it …

This dissertation deals with the development of an optimization framework for kinetic model
building from experimentally measured concentration and spectroscopic data. We develop …

Laboratory automation that drives integrated miniaturized and parallel reactor systems
incorporating analytical devices for online reaction monitoring has reached a remarkable …