The eye is the specialized part of the body and is comprised of numerous physiological
ocular barriers that limit the drug absorption at the action site. Regardless of various efforts …

Sufficient ophthalmic drug delivery is still challenging for pharmaceutical technologists,
despite various scientific efforts. Several ocular drug carriers have been designed to …

Travoprost is a synthetic prostaglandin F2α analogue used in treatment of glaucoma. Due to
its water insolubility and oily nature, novel delivery systems need to be developed to …

Glaucoma is the second leading cause of blindness worldwide. Even though significant
advances have been made in its management, currently available antiglaucoma therapies …

This article proposes an in situ gelling microemulsion for the ocular delivery of moxifloxacin
(MOX) combined with betamethasone (BET) for use as a topical formulation throughout the …

The purpose of this study was to develop and evaluate nanoemulsions (NEs) containing
besifloxacin for ocular drug delivery. Pseudo ternary phase diagrams were constructed …

The aim of this study was to investigate the corneal penetration of brinzolamide (BZ)
nanoemulsions (NEs) and evaluate their in vitro and ex vivo irritancy potential. Twelve BZ …

Objective: The main goal of the present work was to develop and evaluate nanoemulsions
(NEs) containing acyclovir (ACV) for ophthalmic drug delivery. Method: Firstly, component …

Glaucoma, being asymptomatic for relatively late stage, is recognized as a worldwide cause
of irreversible vision loss. The eye is an impervious organ that exhibits natural anatomical …

Brinzolamide is a carbonic anhydrase inhibitor used in the eye drop form for the treatment of
glaucoma. It requires frequent dosing to attain therapeutic concentration. Therefore, this …