[HTML][HTML] Single cell omics in tracing cellular heterogeneity of drug-induced liver injury: technological landscape and prospective application
X Mao, M Xu, X Yan, L Chen, N Lin, Y Zhang - hLife, 2024 - Elsevier
Drug-induced liver injury (DILI) remains a serious problem in clinics for both diagnoses and
treatment decisions. It is a result of accumulated drugs in human bodies metabolized into …
treatment decisions. It is a result of accumulated drugs in human bodies metabolized into …
[HTML][HTML] The impact of G-CSF on mouse immune cells in alcoholic liver disease, focusing on variations in T cells and their subsets
S Park, H Perumalsamy, JE Kim, HY Kim… - Biomedicine & …, 2024 - Elsevier
Alcoholic liver disease (ALD) significantly affects immune cell function and leads to
immunological dysregulation. This study explored the potential of granulocyte colony …
immunological dysregulation. This study explored the potential of granulocyte colony …
Comparison of immune cell profiles associated with heatstroke, sepsis, or cardiopulmonary bypass: Study protocol for an exploratory, case-control study trial
J Wu, S Yang, T Wang, Q Wu, X Liao, R Yao… - Frontiers in …, 2023 - frontiersin.org
Introduction Heatstroke is a life-threatening illness involving extreme hyperthermia and multi-
organ failure, and it is associated with high mortality. The immune profiles of heatstroke have …
organ failure, and it is associated with high mortality. The immune profiles of heatstroke have …
[PDF][PDF] Deciphering the Immunotoxicity of Titanium Dioxide Nanoparticles (E171) in Mouse Leukocytes through Single-Cell RNA Sequencing
H Perumalsamy, X Xiao, HY Han, JH Oh, S Yoon… - 2024 - scholar.archive.org
The cellular and immunological responses in the immune system after exposure to TiO2
NPs/E171 are poorly understood. Therefore, comprehensive single-cell RNA-seq (scRNA …
NPs/E171 are poorly understood. Therefore, comprehensive single-cell RNA-seq (scRNA …
Novel 11β-HSD1 inhibitor ameliorates liver fibrosis by inhibiting the Notch signaling pathway and increasing the NK cell population.
DW Jun, T Yoon, KIM JiEun, Y Kim, J Bae, EL Yoon… - 2024 - researchsquare.com
Abstract 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) regulates hepatic glucose
output and systemic glucose homeostasis. We aimed to investigate the anti-fibrotic effect of a …
output and systemic glucose homeostasis. We aimed to investigate the anti-fibrotic effect of a …
[PDF][PDF] In-depth characterization of early stages of human induced regulatory T cell differentiation by
R Kattelus - 2022 - utupub.fi
The human immune system is complex and well refined system. It consists of two different
parts: innate immunity and adaptive immunity; both are necessary, since they are designed …
parts: innate immunity and adaptive immunity; both are necessary, since they are designed …