Affatoxins, a group of polyketide-derived furanocoumarins (Fig. 1), are the most toxic and
carcinogenic compounds among the known mycotoxins. Among the at least 16 structurally …

Clusters of functionally related genes are a general feature of prokaryotic gene organization
but are much less prevalent in eukaryotes. The discovery that genes for certain types of …

Sterigmatocystin (ST) and the aflatoxins (AFs), related fungal secondary metabolites, are
among the most toxic, mutagenic, and carcinogenic natural products known. The ST …

Enzymology and Molecular Biology of Aflatoxin Biosynthesis | Chemical Reviews ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications …

Aflatoxins are toxic and carcinogenic secondary metabolites produced by the fungi
Aspergillus flavus and A. parasiticus. Aflatoxins are synthesized by condensation of acetate …

The aflatoxins are undoubtedly the most documented of all mycotoxins and have a wide
product presence. While the aflatoxins have at times been detected in most agricultural …

Aflatoxin (AF) and sterigmatocystin (ST) are toxic secondary metabolites produced by the
same biochemical pathway found in several Aspergillus spp. The expression of the …

Aspergillus parasiticus and A. J7avn. r. These ubiquitous fungi are capable of infecting a
wide variety of crops, which, under certain conditions, can become contaminated with this …

An Aspergillus parasiticus gene, designated apa-2, was identified as a regulatory gene
associated with aflatoxin biosynthesis. The apa-2 gene was cloned on the basis of …

An 82-kb Aspergillus parasiticus genomic DNA region representing the completed
sequence of the well-organized aflatoxin pathway gene cluster has been sequenced and …