Innate immune gene polymorphisms in tuberculosis
Tuberculosis (TB) is a leading cause worldwide of human mortality attributable to a single
infectious agent. Recent studies targeting candidate genes and “case-control” association …
infectious agent. Recent studies targeting candidate genes and “case-control” association …
TLR1, 2, 4, 6 and 9 Variants Associated with Tuberculosis Susceptibility: A Systematic Review and Meta-Analysis
Background Studies investigating the influence of toll-like receptor (TLR) polymorphisms
and tuberculosis susceptibility have yielded varying and often contradictory results in …
and tuberculosis susceptibility have yielded varying and often contradictory results in …
Toll-like receptor and TIRAP gene polymorphisms in pulmonary tuberculosis patients of South India
P Selvaraj, M Harishankar, B Singh, MS Jawahar… - Tuberculosis, 2010 - Elsevier
Toll-like receptors (TLRs) are pattern recognition receptors and play an important role in
innate immunity. Changes in TLRs and signaling molecules that result from polymorphisms …
innate immunity. Changes in TLRs and signaling molecules that result from polymorphisms …
Discovery and identification of serum potential biomarkers for pulmonary tuberculosis using iTRAQ‐coupled two‐dimensional LC‐MS/MS
Pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis is a chronic disease.
Currently, there are no sufficiently validated biomarkers for early diagnosis of TB infection. In …
Currently, there are no sufficiently validated biomarkers for early diagnosis of TB infection. In …
The NRAMP1, VDR, TNF-α, ICAM1, TLR2 and TLR4 gene polymorphisms in Iranian patients with pulmonary tuberculosis: A case–control study
The innate immune response drives early events in Mycobacterium tuberculosis infection.
Since human genetic variation is an important determinant in the outcome of infection with …
Since human genetic variation is an important determinant in the outcome of infection with …
Human Toll‐like receptor 4 polymorphisms TLR4 Asp299Gly and Thr399Ile influence susceptibility and severity of pulmonary tuberculosis in the Asian Indian …
Genetic polymorphisms in Toll‐like receptor 4, TLR4 896 A/G (Asp299Gly) and 1196 C/T
(Thr399Ile) have been reported to influence TLR4 function and the innate host immune …
(Thr399Ile) have been reported to influence TLR4 function and the innate host immune …
Influence of Toll‐like receptor gene polymorphisms to tuberculosis susceptibility in humans
S Thada, VL Valluri, SL Gaddam - Scandinavian journal of …, 2013 - Wiley Online Library
Tuberculosis (TB) is caused by M ycobacterium tuberculosis (M. tb), and it remains one of
the major bacterial infections worldwide. Innate immunity is an important arm of …
the major bacterial infections worldwide. Innate immunity is an important arm of …
Association of toll-like receptors 1, 2, 4, 6, 8, 9 and 10 genes polymorphisms and susceptibility to pulmonary tuberculosis in Sudanese patients
NA Mhmoud - ImmunoTargets and Therapy, 2023 - Taylor & Francis
Background Genetic factors are important contributors to the development of a wide range of
complex disease. Polymorphisms in genes encoding for toll-like receptors (TLRs) usually …
complex disease. Polymorphisms in genes encoding for toll-like receptors (TLRs) usually …
Non-Opsonic Recognition of Mycobacterium tuberculosis by Phagocytes
The interactions between Mycobacterium tuberculosis and host phagocytes such as
macrophages and dendritic cells are central to both immunity and pathogenesis. Many …
macrophages and dendritic cells are central to both immunity and pathogenesis. Many …
Gene association with leprosy: a review of published data
PS Mazini, HV Alves, PG Reis, AP Lopes… - Frontiers in …, 2016 - frontiersin.org
Leprosy is a chronic infectious disease caused by an obligate intracellular bacterium known
as Mycobacterium leprae. Exposure to the bacillus is necessary, but this alone does not …
as Mycobacterium leprae. Exposure to the bacillus is necessary, but this alone does not …