Challenges in computational fluid dynamics applications for bone tissue engineering
T Pires, JWC Dunlop… - Proceedings of the …, 2022 - royalsocietypublishing.org
Bone injuries or defects that require invasive surgical treatment are a serious clinical issue,
particularly when it comes to treatment success and effectiveness. Accordingly, bone tissue …
particularly when it comes to treatment success and effectiveness. Accordingly, bone tissue …
Strategy for achieving standardized bone models
M Hadida, D Marchat - Biotechnology and bioengineering, 2020 - Wiley Online Library
Reliably producing functional in vitro organ models, such as organ‐on‐chip systems, has
the potential to considerably advance biology research, drug development time, and …
the potential to considerably advance biology research, drug development time, and …
Histological method to study the effect of shear stress on cell proliferation and tissue morphology in a bioreactor
Background: Tissue engineering represents a promising approach for the production of
bone substitutes. The use of perfusion bioreactors for the culture of bone-forming cells on a …
bone substitutes. The use of perfusion bioreactors for the culture of bone-forming cells on a …
Computational modeling and experimental characterization of fluid dynamics in micro-CT scanned scaffolds within a multiple-sample airlift perfusion bioreactor
The perfusion of flow during cell culture induces cell proliferation and enhances cellular
activity. Perfusion bioreactors offer a controlled dynamic environment for reliable in vitro …
activity. Perfusion bioreactors offer a controlled dynamic environment for reliable in vitro …
In silico regenerative medicine: how computational tools allow regulatory and financial challenges to be addressed in a volatile market
L Geris, Y Guyot, J Schrooten… - Interface …, 2016 - royalsocietypublishing.org
The cell therapy market is a highly volatile one, due to the use of disruptive technologies, the
current economic situation and the small size of the market. In such a market, companies as …
current economic situation and the small size of the market. In such a market, companies as …
Internal flow field analysis of heterogeneous porous scaffold for bone tissue engineering
X Wang, J Chen, Y Guan, L Sun… - Computer methods in …, 2023 - Taylor & Francis
The internal pore structure of the porous scaffold for bone tissue engineering and the
pressure and velocity distributions of its flow field affect the attachment, proliferation and …
pressure and velocity distributions of its flow field affect the attachment, proliferation and …
Assessment of the interplay between scaffold geometry, induced shear stresses, and cell proliferation within a packed bed perfusion bioreactor
By favoring cell proliferation and differentiation, perfusion bioreactors proved efficient at
optimizing cell culture. The aim of this study was to quantify cell proliferation within a …
optimizing cell culture. The aim of this study was to quantify cell proliferation within a …
Numerical simulation of osteoporosis degradation at local scale: a preliminary study on the kinematic loss of mechanical bone stiffness and microstructure
The renewal of living bone is continuous and influenced by many mechanical and biological
factors. A reliable prediction of such phenomena should include many external sources such …
factors. A reliable prediction of such phenomena should include many external sources such …
Channeling Effect and Tissue Morphology in a Perfusion Bioreactor Imaged by X-Ray Microtomography
CC Beauchesne, M Chabanon, B Smaniotto… - Tissue Engineering and …, 2020 - Springer
Background: Perfusion bioreactors for tissue engineering hold great promises. Indeed, the
perfusion of culture medium enhances species transport and mechanically stimulates the …
perfusion of culture medium enhances species transport and mechanically stimulates the …
[PDF][PDF] Channeling effect and tissue morphology in a perfusion bioreactor imaged by X-Ray microtomography Channeling effect and tissue morphology under …
C Beauchesne, M Chabanon, B Smaniotto, B Ladoux… - hal.science
BACKGROUND: Perfusion bioreactors for tissue engineering hold great promises. Indeed,
the perfusion of culture medium enhances species transport and mechanically stimulates …
the perfusion of culture medium enhances species transport and mechanically stimulates …