Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Glycosylated porphyrins, phthalocyanines, and other porphyrinoids for diagnostics and therapeutics

S Singh, A Aggarwal, NVSDK Bhupathiraju… - Chemical …, 2015 - ACS Publications
As deaths from preventable diseases abate, cancer is becoming one of the leading causes
of death in the world. Photodynamic therapy (PDT) is a noninvasive treatment for cancer …

Optically active porphyrin and phthalocyanine systems

H Lu, N Kobayashi - Chemical reviews, 2016 - ACS Publications
This review highlights and summarizes various optically active porphyrin and
phthalocyanine molecules prepared using a wide range of structural modification methods …

Porphyrinoid biohybrid materials as an emerging toolbox for biomedical light management

V Almeida-Marrero, E van de Winckel… - Chemical Society …, 2018 - pubs.rsc.org
The development of photoactive and biocompatible nanomaterials is a current major
challenge of materials science and nanotechnology, as they will contribute to promoting …

Porphyrinoid photosensitizers mediated photodynamic inactivation against bacteria

L Sobotta, P Skupin-Mrugalska, J Piskorz… - European journal of …, 2019 - Elsevier
The multi-drug resistant bacteria have become a serious problem complicating therapies to
such a degree that often the term “post-antibiotic era” is applied to describe the situation …

Single-atom fluorescence switch: a general approach toward visible-light-activated dyes for biological imaging

J Tang, MA Robichaux, KL Wu, J Pei… - Journal of the …, 2019 - ACS Publications
Photoactivatable fluorophores afford powerful molecular tools to improve the spatial and
temporal resolution of subcellular structures and dynamics. By performing a single sulfur-for …

Single-atom replacement as a general approach towards visible-light/near-infrared heavy-atom-free photosensitizers for photodynamic therapy

J Tang, L Wang, A Loredo, C Cole, H Xiao - Chemical Science, 2020 - pubs.rsc.org
Photodynamic therapy has become an emerging strategy for the treatment of cancer. This
technology relies on the development of photosensitizers (PSs) that convert molecular …

Porpholactone chemistry: an emerging approach to bioinspired photosensitizers with tunable near-infrared photophysical properties

Y Ning, GQ Jin, JL Zhang - Accounts of Chemical Research, 2019 - ACS Publications
Conspectus Chlorophylls, known as the key building blocks of natural light-harvesting
antennae, are essential to utilize solar energy from visible to near-infrared (NIR) region …

Gadolinium (III) porpholactones as efficient and robust singlet oxygen photosensitizers

XS Ke, Y Ning, J Tang, JY Hu, HY Yin… - … A European Journal, 2016 - Wiley Online Library
Construction of GdIII photosensitizers is important for designing theranostic agents owing to
the unique properties arising from seven unpaired f electrons of the Gd3+ ion. Combining …

Porphodilactones as synthetic chlorophylls: Relative orientation of β-substituents on a pyrrolic ring tunes NIR absorption

XS Ke, Y Chang, JZ Chen, J Tian, J Mack… - Journal of the …, 2014 - ACS Publications
Porphodilactones represent the porphyrin analogues, in which the peripheral bonds of two
pyrrole rings are replaced by lactone moieties. They provide an opportunity to investigate …