The European Registry on Obstetric Antiphospholipid Syndrome (EUROAPS): a survey of 1000 consecutive cases

J Alijotas-Reig, E Esteve-Valverde… - Autoimmunity …, 2019 - Elsevier
Aim To analyse the clinical features, laboratory data and foetal-maternal outcomes, and
follow them up on a cohort of 1000 women with obstetric antiphospholipid syndrome …

Role of infectious diseases in the antiphospholipid syndrome (including its catastrophic variant)

C Mendoza-Pinto, M García-Carrasco… - Current rheumatology …, 2018 - Springer
Abstract Purpose of Review The antiphospholipid syndrome (APS) is characterized by the
development of thrombotic events and pregnancy morbidity in the presence of …

[HTML][HTML] Deciphering the clinical significance of longitudinal antiphospholipid antibody titers

CB Chighizola, R Willis, G Maioli, S Sciascia… - Autoimmunity …, 2024 - Elsevier
In antiphospholipid syndrome (APS), the risk of clinical manifestations increases with higher
titers of antiphospholipid antibodies (aPL). Despite the adoption of aPL titers in the …

Can anticoagulation be withdrawn in APS patients after aPL negativization?

MJ Cuadrado, A Tincani, EE Merayo, L Moschetti… - Autoimmunity …, 2024 - Elsevier
Long-term vitamin K antagonist (VKA) anticoagulation is the cornerstone of the management
of subjects with thrombotic antiphospholipid syndrome (APS). Recent investigations have …

Prevalence of antiphospholipid antibodies negativisation in patients with antiphospholipid syndrome: a long-term follow-up multicentre study

M Radin, K Schreiber, S Sciascia… - Thrombosis and …, 2019 - thieme-connect.com
Objective This article aims to analyse the rate of antiphospholipid antibodies (aPL)
negativisation in patients with antiphospholipid syndrome (APS), and to evaluate potential …

Prevalence, outcome and management of patients with SLE and secondary antiphospholipid antibody syndrome after aPL seroconversion

M Zen, M Loredo Martinez, F Benvenuti, M Gatto… - …, 2021 - academic.oup.com
Objective The withdrawal of oral anticoagulation (OAC) in patients with SLE and secondary
aPL syndrome (SAPS) who become seronegative has not been clearly investigated to date …

Pediatric antiphospholipid syndrome: clinical features and therapeutic interventions in a single center retrospective case series

JA Madison, K Gockman, C Hoy, A Tambralli… - Pediatric …, 2022 - Springer
Background/purpose Pediatric antiphospholipid syndrome (APS) is a thromboinflammatory
disease characterized by the presence of circulating antiphospholipid antibodies and either …

Management of patients with antiphospholipid antibodies: What to do in laboratory scenarios that do not fit the guidelines

G Pires Da Rosa, I Rodríguez-Pintó… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Some patients with positive antiphospholipid antibodies (aPL) have not been
included in randomized clinical trials or observational registries and, therefore, information …

Treatment of thrombotic antiphospholipid syndrome in adults and children

JA Madison, A Duarte-García, Y Zuo… - Current opinion in …, 2020 - journals.lww.com
Progress continues to be made in pursuit of improving the lives of individuals afflicted with
APS. The most important future directions would seem to involve leveraging modern …

Can we withdraw anticoagulation in patients with antiphospholipid syndrome after seroconvertion?

S Sciascia, E Coloma-Bazán, M Radin… - Autoimmunity …, 2017 - Elsevier
The current mainstay of treatment in patients with thrombotic antiphospholipid syndrome
(APS) is long-term anticoagulation, mainly with Vitamin K antagonist agents. Some recently …