In vivo neuroplasticity in vestibular animal models

A Zwergal, M Lindner, M Grosch, M Dieterich - Molecular and Cellular …, 2022 - Elsevier
An acute unilateral vestibulopathy leads to symptoms of vestibular tone imbalance, which
gradually decrease over days to weeks due to central vestibular compensation. Animal …

Plastic Events of the Vestibular Nucleus: the Initiation of Central Vestibular Compensation

J Wu, X Xu, S Zhang, M Li, Y Qiu, G Lu, Z Zheng… - Molecular …, 2024 - Springer
Vestibular compensation is a physiological response of the vestibular organs within the
inner ear. This adaptation manifests during consistent exposure to acceleration or …

Sensorimotor rehabilitation promotes vestibular compensation in a rodent model of acute peripheral vestibulopathy by promoting microgliogenesis in the deafferented …

E Marouane, N El Mahmoudi, G Rastoldo, D Péricat… - Cells, 2021 - mdpi.com
Acute peripheral vestibulopathy leads to a cascade of symptoms involving balance and gait
disorders that are particularly disabling for vestibular patients. Vestibular rehabilitation …

Microglial dynamics modulate vestibular compensation in a rodent model of vestibulopathy and condition the expression of plasticity mechanisms in the deafferented …

N El Mahmoudi, E Marouane, G Rastoldo, D Pericat… - Cells, 2022 - mdpi.com
Unilateral vestibular loss (UVL) induces a vestibular syndrome composed of posturo-
locomotor, oculomotor, vegetative, and perceptivo-cognitive symptoms. With time, these …

Long-lasting spatial memory deficits and impaired hippocampal plasticity following unilateral vestibular loss

N El Mahmoudi, C Laurent, D Péricat, I Watabe… - Progress in …, 2023 - Elsevier
Unilateral vestibular loss (UVL) induces a characteristic vestibular syndrome composed of
various posturo-locomotor, oculomotor, vegetative and perceptivo-cognitive symptoms …

Characterization of thyroid hormones antivertigo effects in a rat model of excitotoxically-induced vestibulopathy

CM Bringuier, B Hatat, R Boularand… - Frontiers in …, 2022 - frontiersin.org
Impaired vestibular function induces disabling symptoms such as postural imbalance,
impaired locomotion, vestibulo-ocular reflex alteration, impaired cognitive functions such as …

[HTML][HTML] Molecular profile of vestibular compensation in the medial vestibular nucleus after unilateral labyrinthectomy

J Wang, D Liu, E Tian, Y Zhang, Z Guo… - Journal of Cellular …, 2024 - ncbi.nlm.nih.gov
Long non‐coding RNAs (lncRNAs) have emerged as crucial regulators in the central
nervous system, yet their role in vestibular compensation remains elusive. To address this …

The Vestibular Nuclei: A Cerebral Reservoir of Stem Cells Involved in Balance Function in Normal and Pathological Conditions

G Rastoldo, B Tighilet - International Journal of Molecular Sciences, 2024 - mdpi.com
In this review, we explore the intriguing realm of neurogenesis in the vestibular nuclei—a
critical brainstem region governing balance and spatial orientation. We retrace almost 20 …

What Predictability for Animal Models of Peripheral Vestibular Disorders?

B Tighilet, J Trico, F Xavier, C Chabbert - Biomedicines, 2022 - mdpi.com
The different clinical entities grouped under the term peripheral vestibulopathies (PVs) or
peripheral vestibular disorders (PVDs) are distinguished mainly based on their …

Histaminergic System and Vestibular Function in Normal and Pathological Conditions

B Tighilet, J Trico, E Marouane… - Current …, 2024 - ingentaconnect.com
Most neurotransmitter systems are represented in the central and peripheral vestibular
system and are thereby involved both in normal vestibular signal processing and the …