Interactions with microbial proteins driving the antibacterial activity of flavonoids

G Donadio, F Mensitieri, V Santoro, V Parisi… - Pharmaceutics, 2021 - mdpi.com
Flavonoids are among the most abundant natural bioactive compounds produced by plants.
Many different activities have been reported for these secondary metabolites against …

From nature's bounty to drug discovery: Leveraging phytochemicals and molecular approaches to combat multi-drug-resistant (MDR) tuberculosis

SM Nalam, PK Chintamaneni, RS Pal… - Indian Journal of …, 2024 - Elsevier
A large number of people annually lose their lives to tuberculosis (TB), which is an age-old
disease caused by the Mycobacterium tuberculosis. The global spread of TB is a concern for …

Multifunctional analysis and antimicrobial activity of Adhatoda vasica: a traditional medicinal plant

M Fatima, I Zafar, Q Ain, MM Anwar… - Drug Metabolism and …, 2024 - degruyter.com
Objectives Antibiotic resistance is rising, prompting innovative strategies for eradicating the
epidemic. This study investigated the antibacterial properties of the leaves of a widely used …

Adhatoda vasica and Tinospora cordifolia extracts ameliorate clinical and molecular markers in mild COVID-19 patients: a randomized open-label three-armed study

M Verma, N Rawat, R Rani, M Singh… - European Journal of …, 2023 - Springer
Background SARS-CoV-2 infections caused mild-to-moderate illness. However, a sizable
portion of infected people experience a rapid progression of hyper-inflammatory and …

Valorization of Adhatoda vasica leaves: Extraction, in vitro analyses and in silico approaches

M Rudrapal, S Vallinayagam, S Aldosari, J Khan… - Frontiers in …, 2023 - frontiersin.org
Adhatoda vasica (also called Vasaka) is a traditional medicinal herb used traditionally for
the relief of cough, asthma, nasal congestion, bronchial inflammation, upper respiratory …

[HTML][HTML] Recent advances in application of computer-aided drug design in anti-COVID-19 Virials Drug Discovery

W Yang, Y Wang, D Han, W Tang, L Sun - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Abstract Corona Virus Disease 2019 (COVID-19) is a global pandemic epidemic caused by
severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which poses a …

Phytochemical Characterization and Assessment of Crude Extracts from Justicia adhatoda for Phytotoxic and Cytotoxic Activity

M Nasir, R Ramash, H Fatima, S Ashraf, I Munir… - …, 2024 - Wiley Online Library
Background. The aim of the study was to investigate the cytotoxicity, phytotoxicity, and
proximate and phytochemical analysis of methanolic extracts of the leaves of Justicia …

[PDF][PDF] A review of molecular investigations on traditional Chinese medicinal plant-based therapies in multidrug-resistant tuberculosis

K Singh, D Jain, M Chaitanya… - Pharmacological …, 2024 - researchgate.net
Introduction: The escalating threat of drug-resistant tuberculosis (TB) necessitates urgent
exploration of alternative treatment methods. Traditional Chinese medicinal (TCM) plants …

Microwave-assisted extraction of flavonoids from phyllostachys heterocycla leaves: Optimization, mechanism, and antioxidant activity in vitro

J Xu, J Wu, J Qi, J Li, Y Liu, Z Miao, G Qiu… - …, 2021 - search.proquest.com
Flavonoids were extracted from Phyllostachys heterocycla leaves by adopting microwave-
assisted extraction technology. Based on the single factor experiment and Plackett-Burman …

Ethnobotanical notes and pharmacological overview of traditional plant: Adhatoda vasica

A Biharee, S Bhartiya, D Dubey… - Dermatological …, 2023 - Wiley Online Library
Abstract Background Adhatoda vasica (Nees.) of the Acanthaceae family has excellent
medicinal properties. It is a crucial ingredient in a number of formulations that have been …