Rheumatoid arthritis (RA) is a common, chronic, systemic autoimmune disease, and its
clinical features are the proliferation of joint synovial tissue, the formation of pannus and the …

The initiation and development of major inflammatory diseases, ie, cancer, vascular
inflammation, and some autoimmune diseases are closely linked to the immune system …

Regulatory B cells (Bregs) ameliorate autoimmune disease and prevent allograft rejection.
Conversely, they hinder effective clearance of pathogens and malignancies. Breg activity is …

Immune-mediated inflammatory diseases (IMIDs), such as spondyloarthritis (SpA), psoriasis,
Crohn's disease (CD), and rheumatoid arthritis (RA) remain challenging illnesses. They …

Regulatory B (Breg) cells are characterized by differential expression of CD5 and CD1d in
mouse and CD24 and CD38 in human immune systems. The Breg family also includes LAG …

Immune-mediated inflammatory diseases, such as rheumatoid arthritis, psoriatic arthritis,
peripheral and/or axial spondyloarthritis, Crohn's disease, and ulcerative colitis, are …

Early immunological biomarkers that predict rejection and chronic allograft loss are needed
to inform preemptive therapy and improve long-term outcomes. Here, we prospectively …

Abstract Objective Regulatory B cells (Bregs) are a new subset of B cells with
immunoregulatory functions, mainly through IL-10 production. Bregs suppress inflammatory …

Purpose The aim of this article was to review published research related to B lymphocytes in
rheumatoid arthritis, their role in the pathogenesis of the disease, the effects of tumor …

Our understanding of the B-cell subsets found in human blood and their functional
significance has advanced greatly in the past decade. This has been aided by the evolution …