Current role of primary surgical treatment in patients with head and neck squamous cell carcinoma

A Bozec, D Culié, G Poissonnet… - Current opinion in …, 2019 - journals.lww.com
Surgery should be the primary treatment modality for most resectable oral cavity cancers
and for T4a laryngeal/hypopharyngeal cancers. Primary surgery could also be the preferred …

The current burden of oropharyngeal cancer: a global assessment based on GLOBOCAN 2020

V Lorenzoni, AK Chaturvedi, J Vignat… - … Biomarkers & Prevention, 2022 - AACR
Background: Oropharyngeal cancer (OPC) is a complex disease whose etiologies, either
related to risk factors such as smoking or alcohol, or linked to HPV infection, are believed to …

Targeted inhibition of eIF5Ahpu suppresses tumor growth and polarization of M2-like tumor-associated macrophages in oral cancer

J Zeng, Z Ye, S Shi, Y Liang, Q Meng, Q Zhang… - Cell Death & …, 2023 - nature.com
Eukaryotic initiation factor 5A2 (eIF5A2) is overexpressed in many types of cancer, and
spermidine-mediated eIF5A hypusination (eIF5Ahpu) appears to be essential to most of …

Transoral robotic surgery for head and neck malignancies: Imaging features in presurgical workup

BYM Kwan, NM Khan, JR de Almeida… - Head & …, 2019 - Wiley Online Library
The objective of this article was to review the indications for transoral robotic surgery (TORS)
in head and neck malignancies. The role of imaging in patient selection will be specifically …

Risk factors for overall survival outcome in surgically treated human papillomavirus-negative and positive patients with oropharyngeal cancer

N Wuerdemann, C Wittekindt, SJ Sharma… - Oncology Research …, 2017 - karger.com
Introduction: This study reports the oncological outcome of a non-selected series of patients
with human papillomavirus (HPV)-positive and-negative oropharyngeal squamous cell …

Long‐term analysis of transorally resected p16+ oropharynx cancer: outcomes and prognostic factors

P Sinha, BH Haughey, D Kallogjeri… - The …, 2019 - Wiley Online Library
Objective We observed high survival in a previous report of a p16‐positive, oropharyngeal
carcinoma (OPC) cohort treated primarily with transoral laser microsurgery (TLM)±adjuvant …

Twist and snail/slug expression in oropharyngeal squamous cell carcinoma in correlation with lymph node metastasis

YA Cho, EK Kim, BC Cho, YW Koh… - Anticancer research, 2019 - ar.iiarjournals.org
Background/Aim: Oropharyngeal squamous cell carcinoma (OPSCC) could be clinically
undetectable despite the relatively large size of lymph node metastases. Here, we aimed to …

Treatment trends in oropharyngeal carcinoma: surgical technology meets the epidemic

TJ Gal, JA Slezak, AE Kejner, Q Chen, B Huang - Oral oncology, 2019 - Elsevier
Objective To characterize temporal trends in treatment patterns for oropharyngeal
carcinoma, and to evaluate the emerging role of surgical therapy in the era of transoral …

Histopathological Prognostic Factors of Surgically Treated HPV-Associated Oropharyngeal Squamous Cell Carcinoma: A Systematic Review and Meta-analysis

BQY Chua, VWS Chong, HBA Kadir, BSY Yeo… - Annals of Surgical …, 2024 - Springer
Background Human papilloma virus (HPV)-positive oropharyngeal squamous cell
carcinoma (OPSCC) is rising in prevalence and is associated with better survival than HPV …

Machine Learning Methods in Classification of Prolonged Radiation Therapy in Oropharyngeal Cancer: National Cancer Database

S Ahn, EJ Oh, MI Saleem… - Otolaryngology–Head and …, 2024 - Wiley Online Library
Objective To investigate the accuracy of machine learning (ML) algorithms in stratifying risk
of prolonged radiation treatment duration (RTD), defined as greater than 50 days, for …