This review provides an outline of the association between major depressive disorder
(MDD) and coronary heart disease (CHD). Much is known about the two individual clinical …

Several articles have dealt with the importance and mechanisms of the sympathetic nervous
system alterations in experimental animal models of hypertension. This review addresses …

Recent clinical trial data suggest a cardiorenal protective effect of sodium glucose
cotransporter 2 (SGLT2) inhibition. We demonstrate that chemical denervation in neurogenic …

Approximately half of all patients with heart failure have preserved ejection fraction (HFpEF)
and, as life expectancies continue to increase in western societies, the prevalence of HFpEF …

The gasotransmitters are a family of gaseous signaling molecules which are produced
endogenously and act at specific receptors to play imperative roles in physiologic and …

Physiological studies have long documented the key role played by the autonomic nervous
system in modulating cardiovascular functions and in controlling blood pressure values …

Background Cardiovascular disease remains the leading worldwide cause of mortality.
There has been increased awareness of the impact of psychological health on …

Background: It has long been known that depression is associated with hypertension but
whether depression is a risk factor for hypertension incidence is still inconclusive …

Evidence assembled in this review indicates that sympathetic nervous system dysfunction is
crucial in the development of heart failure and essential hypertension. This takes the form of …

Background: The sympathetic nervous system (SNS) regulates glucose metabolism in
various organs including the kidneys. The sodium glucose cotransporter 2 (SGLT2) …