Objectives To estimate procedure‐related risks of miscarriage following amniocentesis and
chorionic villus sampling (CVS) based on a systematic review of the literature and a meta …

Background During pregnancy, fetal cells suitable for genetic testing can be obtained from
amniotic fluid by amniocentesis (AC), placental tissue by chorionic villus sampling (CVS), or …

Disclaimer: This statement is designed primarily as an educational resource for clinicians to
help them provide quality medical services. Adherence to this statement is completely …

The rate of twin pregnancies in the United States has stabilized at 32 per 1000 births in
2006. Aside from determining chorionicity, first-trimester screening and second-trimester …

Introduction: As a consequence of the introduction of effective screening methods, the
number of invasive prenatal diagnostic procedures is steadily declining. The aim of this …

Context: Congenital adrenal hyperplasia (CAH) is an autosomal recessive condition that
arises from mutations in CYP21A2 gene, which encodes for the steroidogenic enzyme 21 …

Context Noninvasive prenatal determination of fetal sex using cell-free fetal DNA provides
an alternative to invasive techniques for some heritable disorders. In some countries this …

Objective To assess prospectively the risk of fetal loss associated with chorionic villus
sampling (CVS) and amniocentesis (AC) following combined first‐trimester screening (cFTS) …

BACKGROUND Cell-free fetal nucleic acids (cffNA) can be detected in the maternal
circulation during pregnancy, potentially offering an excellent method for early non-invasive …

Plasma is a rich mine of various biomarkers including proteins, metabolites and circulating
nucleic acids. The diagnostic and therapeutic potential of these analytes has been quite …