Ageing and atherosclerosis: vascular intrinsic and extrinsic factors and potential role of IL-6

DJ Tyrrell, DR Goldstein - Nature Reviews Cardiology, 2021 - nature.com
The number of old people is rising worldwide, and advancing age is a major risk factor for
atherosclerotic cardiovascular disease. However, the mechanisms underlying this …

Mechanisms of vascular aging

Z Ungvari, S Tarantini, AJ Donato, V Galvan… - Circulation …, 2018 - Am Heart Assoc
Aging of the vasculature plays a central role in morbidity and mortality of older people. To
develop novel treatments for amelioration of unsuccessful vascular aging and prevention of …

Endothelial cell metabolism

G Eelen, P de Zeeuw, L Treps, U Harjes… - Physiological …, 2018 - journals.physiology.org
Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

Heterogeneity of mesenchymal stem cells in cartilage regeneration: from characterization to application

K Zha, X Li, Z Yang, G Tian, Z Sun, X Sui… - NPJ Regenerative …, 2021 - nature.com
Articular cartilage is susceptible to damage but hard to self-repair due to its avascular
nature. Traditional treatment methods are not able to produce satisfactory effects …

The adverse effects of environmental noise exposure on oxidative stress and cardiovascular risk

T Münzel, M Sørensen, F Schmidt… - Antioxidants & redox …, 2018 - liebertpub.com
Epidemiological studies have provided evidence that traffic noise exposure is linked to
cardiovascular diseases such as arterial hypertension, myocardial infarction, and stroke …

New insight into dyslipidemia‐induced cellular senescence in atherosclerosis

Q Xiang, F Tian, J Xu, X Du, S Zhang… - Biological Reviews, 2022 - Wiley Online Library
Atherosclerosis, characterized by lipid‐rich plaques in the arterial wall, is an age‐related
disorder and a leading cause of mortality worldwide. However, the specific mechanisms …

Molecular biology of atherosclerosis

PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Circulating endothelial progenitor cells and cardiovascular outcomes

N Werner, S Kosiol, T Schiegl, P Ahlers… - … England Journal of …, 2005 - Mass Medical Soc
Background Endothelial progenitor cells derived from bone marrow are believed to support
the integrity of the vascular endothelium. The number and function of endothelial progenitor …

Endothelial progenitor cells: characterization and role in vascular biology

C Urbich, S Dimmeler - Circulation research, 2004 - Am Heart Assoc
Infusion of different hematopoietic stem cell populations and ex vivo expanded endothelial
progenitor cells augments neovascularization of tissue after ischemia and contributes to …

Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in …

R Madonna, LW Van Laake, SM Davidson… - European heart …, 2016 - academic.oup.com
Despite improvements in modern cardiovascular therapy, the morbidity and mortality of
ischaemic heart disease (IHD) and heart failure (HF) remain significant in Europe and …