Primary microcephaly (MCPH), is a neurological disorder characterized by small brain size
that results in numerous developmental problems, including intellectual disability, motor and …

Congenital microcephaly (CM) exhibits broad clinical and genetic heterogeneity and is thus
categorized into several subtypes. However, the recent bloom of disease–gene discoveries …

Primary microcephalies (PMs) are defects in brain growth that are detectable at or before
birth and are responsible for neurodevelopmental disorders. Most are caused by biallelic or …

Background Breast cancer subtypes are statistically associated with prognosis. The search
for markers of breast tumor heterogeneity and the development of precision medicine for …

Congenital microcephaly is the clinical presentation of significantly reduced head
circumference at birth. It manifests as both non-syndromic—microcephaly primary hereditary …

The c-Jun N-terminal kinase (JNK) is highly evolutionarily conserved and plays important
roles in a broad range of physiological and pathological processes. The WD40-repeat …

Microcephaly (MCPH) is a developmental anomaly of the brain known by reduced cerebral
cortex and underdeveloped intellectual disability without additional clinical symptoms. It is a …

Aims: Autosomal recessive primary microcephaly (MCPH) is a clinically rare and genetically
highly heterogeneous developmental disorder. Biallelic variants in the abnormal spindle-like …

Purpose Neurodevelopmental disorders exhibit clinical and genetic heterogeneity, ergo
manifest dysfunction in components of diverse cellular pathways; the precise …

Methods: We studied two unrelated consanguineous families (family A and B) presenting> 2
patients with diagnostic symptoms of MCPH, born to asymptomatic parents. We employed …