Mesoporous silica nanoparticles: synthesis, pharmaceutical applications, biodistribution, and biosafety assessment

F Farjadian, A Roointan, S Mohammadi-Samani… - Chemical Engineering …, 2019 - Elsevier
Mesoporous silica nanoparticles (MSNs) are a key example of the innovation in material
science to develop nanotechnology-based delivery systems. Biological and pharmaceutical …

Water soluble polymers for pharmaceutical applications

VG Kadajji, GV Betageri - Polymers, 2011 - mdpi.com
Advances in polymer science have led to the development of novel drug delivery systems.
Some polymers are obtained from natural resources and then chemically modified for …

The influence of nanoparticle properties on oral bioavailability of drugs

Y Wang, C Pi, X Feng, Y Hou, L Zhao… - International journal of …, 2020 - Taylor & Francis
Oral administration has been the most common therapeutic regimen in various diseases
because of its high safety, convenience, lower costs, and high compliance of patients …

Chitosan-based drug nanocarriers: where do we stand?

M Garcia-Fuentes, MJ Alonso - Journal of Controlled Release, 2012 - Elsevier
Chitosan-based nanocarriers have become one of the most intensively studied
transmucosal nanometric drug delivery platforms. This is due to a number of factors …

Chitosan nanoparticles: a survey of preparation methods

A Grenha - Journal of drug targeting, 2012 - Taylor & Francis
The application of macromolecules in therapy is frequently hindered by stability and/or
permeation issues. These limitations have been addressed by the pharmaceutical industry …

Role of sustained antigen release from nanoparticle vaccines in shaping the T cell memory phenotype

SL Demento, W Cui, JM Criscione, E Stern, J Tulipan… - Biomaterials, 2012 - Elsevier
Particulate vaccines are emerging promising technologies for the creation of tunable
prophylactics against a wide variety of conditions. Vesicular and solid biodegradable …

New developments and opportunities in oral mucosal drug delivery for local and systemic disease

V Hearnden, V Sankar, K Hull, DV Juras… - Advanced drug delivery …, 2012 - Elsevier
The oral mucosa's accessibility, excellent blood supply, by-pass of hepatic first-pass
metabolism, rapid repair and permeability profile make it an attractive site for local and …

Chitosan-based nanostructures: a delivery platform for ocular therapeutics

M de la Fuente, M Raviña, P Paolicelli… - Advanced drug delivery …, 2010 - Elsevier
Nanoscience and nanotechnology has caused important breakthroughs in different
therapeutic areas. In particular, the application of nanotechnology in ophthalmology has led …

Mucus penetrating nanoparticles: biophysical tool and method of drug and gene delivery

LM Ensign, C Schneider, JS Suk, R Cone… - Advanced …, 2012 - Wiley Online Library
A method that could provide more uniform and longer‐lasting drug and gene delivery to
mucosal surfaces holds the potential to greatly improve the effectiveness of prophylactic and …

Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery

KT Mody, A Popat, D Mahony, AS Cavallaro, C Yu… - Nanoscale, 2013 - pubs.rsc.org
Vaccines have been at the forefront of improving human health for over two centuries. The
challenges faced in developing effective vaccines flow from complexities associated with the …