Abstract Alzheimer's disease (AD), the most common cause of dementia, results in a
sustained decline in cognition. There are currently few effective disease modifying therapies …

The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

Tau-mediated neurodegeneration is a hallmark of Alzheimer's disease. Primary tauopathies
are characterized by pathological tau accumulation and neuronal and synaptic loss …

Dysregulation of the immune system is a cardinal feature of Alzheimer disease (AD), and a
considerable body of evidence indicates pathological alterations in central and peripheral …

Objective This study is to investigate the role of gut dysbiosis in triggering inflammation in
the brain and its contribution to Alzheimer's disease (AD) pathogenesis. Design We …

Background The implication of gut microbiota in the control of brain functions in health and
disease is a novel, currently emerging concept. Accumulating data suggest that the gut …

Research into the role of the gut microbiome in modulating brain function has rapidly
increased over the past 10 years, albeit chiefly in animal models. Increasing clinical and …

Recently, increasing evidence has suggested the association between gut dysbiosis and
Alzheimer's disease (AD) progression, yet the role of gut microbiota in AD pathogenesis …

Gut microbiota is emerging as a key regulator of many disease conditions and its
dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal …

Previous studies have identified a crucial role of the gut microbiome in modifying
Alzheimer's disease (AD) progression. However, the mechanisms of microbiome–brain …