Obsessive–compulsive disorder (OCD) is characterized by repetitive thoughts and
behaviours that are experienced as unwanted. Family and twin studies have demonstrated …

Netrins are secreted proteins that were first identified as guidance cues, directing cell and
axon migration during neural development. Subsequent findings have demonstrated that …

Obsessive-compulsive disorder (OCD) is a psychiatric condition characterized by intrusive
thoughts and urges and repetitive, intentional behaviors that cause significant distress and …

Synapse development requires differentiation of presynaptic neurotransmitter release sites
and postsynaptic receptive apparatus coordinated by synapse organizing proteins. In …

A number of synaptogenic factors induce presynaptic or postsynaptic differentiation when
presented to axons or dendrites. Many such factors participate in bidirectional trans-synaptic …

Balanced development of excitatory and inhibitory synapses is required for normal brain
function, and an imbalance in this development may underlie the pathogenesis of many …

Neurotrophin receptor tyrosine kinases (Trks) have well-defined trophic roles in nervous
system development through kinase activation by neurotrophins. Yet Trks have typical cell …

Heparan sulfate proteoglycans (HSPGs) are components of the cell surface and
extracellular matrix, which bear long polysaccharides called heparan sulfate (HS) attached …

Protein tyrosine phosphatases (PTP s) represent a super‐family of enzymes that play
essential roles in normal development and physiology. In this review, we will discuss the …

The synapse is the most elementary operating unit in neurons, creating neural circuits that
underlie all brain functions. Synaptic adhesion molecules initiate neuronal synapse …