Metabolic dysfunction-associated steatotic liver disease (MASLD) is a complex multifactorial
disease and becoming the leading cause of liver-related morbidity and mortality. MASLD …

Metabolic dysfunction–associated steatotic liver disease (MASLD) is a growing global health
problem, affecting∼ 1 billion people. This condition is well established to have a heritable …

Non-alcoholic fatty liver disease (NAFLD) is a common and prevalent disorder affecting 25
percent of the adults in the United States and 32 percent of adults globally. It is one of the …

Steatotic liver disease (SLD) prevails as the most common chronic liver disease yet lack
approved treatments due to incomplete understanding of pathogenesis. Recently, elevated …

Much more than a histological feature, lipid droplets are complex heterogenous organelles
crucial to cellular metabolism with important causative roles in the development and …

Over the past 10 years, the biological role of lipid droplets (LDs) has gained significant
attention in the context of both physiological and pathological conditions. Considerable …

Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) is the most prevalent
chronic liver disease and the major cause of liver-related mortality worldwide 1. MASLD is …

Abbreviations: ER, endoplasmic reticulum; HFD, high-fat diet; MASLD, metabolic dysfunction-
associated steatotic liver disease; MBOAT7, membrane bound O-acyltransferase domain …

Background Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM)
are associated with a multifactorial complicated aetiology that is often coexisting and has a …

Metabolic dysfunction-associated steatotic liver disease (MASLD), is the most common
cause of liver disease, and its burden on health systems worldwide continues to rise at an …