Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …

Every cell in nature carries a rich surface coat of glycans, its glycocalyx, which constitutes
the cell's interface with its environment. In eukaryotes, the glycocalyx is composed of …

Oligodendrocytes, the myelin-forming cells of the central nervous system (CNS), and
astrocytes constitute macroglia. This review deals with the recent progress related to the …

In addition to their role in providing myelin for rapid impulse propagation, the glia that
ensheath long axons are required for the maintenance of normal axon transport and long …

For many decades, the inability of lesioned central neurons to regrow was accepted almost
as a" law of nature", and on the clinical level, spinal cord and brain lesions were seen as …

Numerous lines of inquiry implicate connectivity as a central abnormality in schizophrenia.
Myelination and factors that affect myelination, such as the function of oligodendroglia, are …

Following nerve injury, axons in the CNS do not normally regenerate. It has been shown that
CNS myelin inhibits neurite outgrowth, though the nature of the molecules responsible for …

Oligodendrocytes and Schwann cells are highly specialized glial cells that wrap axons with
a multilayered myelin membrane for rapid impulse conduction. Investigators have recently …

The vertebrate nervous system is characterized by ensheathment of axons with myelin, a
multilamellar membrane greatly enriched in the galactolipid galactocerebroside (GalC) and …

Multiple sclerosis (MS) is an inflammatory demyelinating disease that is considered by many
people to have an autoimmune aetiology. In recent years, new data emerging from …