SARS-CoV-2 RNA-dependent RNA polymerase as a therapeutic target for COVID-19
ABSTRACT Introduction: The current SARS-CoV-2 pandemic urgently demands for both
prevention and treatment strategies. RNA-dependent RNA-polymerase (RdRp), which has …
prevention and treatment strategies. RNA-dependent RNA-polymerase (RdRp), which has …
Pathogenicity and virulence of Marburg virus
Marburg virus (MARV) has been a major concern since 1967, with two major outbreaks
occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever …
occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever …
Pharmacological treatment of COVID-19: an opinion paper
A García-Lledó, J Gómez-Pavón… - Revista Española …, 2021 - pmc.ncbi.nlm.nih.gov
The precocity and efficacy of the vaccines developed so far against COVID-19 has been the
most significant and saving advance against the pandemic. The development of vaccines …
most significant and saving advance against the pandemic. The development of vaccines …
An introduction to the Marburg virus vaccine consortium, MARVAC
The emergence of Marburg virus (MARV) in Guinea and Ghana triggered the assembly of
the MARV vaccine “MARVAC” consortium representing leaders in the field of vaccine …
the MARV vaccine “MARVAC” consortium representing leaders in the field of vaccine …
Emerging and reemerging infectious diseases: global trends and new strategies for their prevention and control
S Wang, W Li, Z Wang, W Yang, E Li, X Xia… - Signal transduction and …, 2024 - nature.com
To adequately prepare for potential hazards caused by emerging and reemerging infectious
diseases, the WHO has issued a list of high-priority pathogens that are likely to cause future …
diseases, the WHO has issued a list of high-priority pathogens that are likely to cause future …
[HTML][HTML] Marburg virus disease: a summary for clinicians
MG Kortepeter, K Dierberg, ES Shenoy… - International Journal of …, 2020 - Elsevier
Objectives This article summarizes the countermeasures for Marburg virus disease, focusing
on pathogenesis, clinical features and diagnostics. There is an emphasis on therapies and …
on pathogenesis, clinical features and diagnostics. There is an emphasis on therapies and …
Marburg virus disease: a deadly rare virus is coming
F Zhao, Y He, H Lu - Bioscience trends, 2022 - jstage.jst.go.jp
Two cases of the deadly Marburgvirus were reported in Ghana, which might be a new global
virus alert following COVID-19 and novel monkeypox. Thus far, there is no vaccine or …
virus alert following COVID-19 and novel monkeypox. Thus far, there is no vaccine or …
Emergence of Marburg virus: a global perspective on fatal outbreaks and clinical challenges
The Marburg virus (MV), identified in 1967, has caused deadly outbreaks worldwide, the
mortality rate of Marburg virus disease (MVD) varies depending on the outbreak and virus …
mortality rate of Marburg virus disease (MVD) varies depending on the outbreak and virus …
Oral obeldesivir provides postexposure protection against Marburg virus in nonhuman primates
The recent outbreak of Marburg virus (MARV) in Rwanda underscores the need for effective
countermeasures against this highly fatal pathogen, with case fatality rates reaching 90 …
countermeasures against this highly fatal pathogen, with case fatality rates reaching 90 …
Expanded profiling of Remdesivir as a broad-spectrum antiviral and low potential for interaction with other medications in vitro
SR Radoshitzky, P Iversen, X Lu, J Zou, SJF Kaptein… - Scientific reports, 2023 - nature.com
Abstract Remdesivir (GS-5734; VEKLURY) is a single diastereomer monophosphoramidate
prodrug of an adenosine analog (GS-441524). Remdesivir is taken up by target cells and …
prodrug of an adenosine analog (GS-441524). Remdesivir is taken up by target cells and …