ACG clinical guideline for the diagnosis and management of gastroesophageal reflux disease
Gastroesophageal reflux disease (GERD) continues to be among the most common
diseases seen by gastroenterologists, surgeons, and primary care physicians. Our …
diseases seen by gastroenterologists, surgeons, and primary care physicians. Our …
Long-term use of proton pump inhibitors as a risk factor for various adverse manifestations
A Koyyada - Therapies, 2021 - Elsevier
The long-term use of proton pump inhibitors (PPIs) can lead to increased gastric pH,
hypochlorhydria and in some cases to achlorhydria when compared to other acid …
hypochlorhydria and in some cases to achlorhydria when compared to other acid …
The use and misuse of proton pump inhibitors: an opportunity for deprescribing
TS Dharmarajan - Journal of the American Medical Directors Association, 2021 - Elsevier
Proton pump inhibitors (PPIs) are proven medications of choice for gastroesophageal reflux
disease (GERD), acid-related disorders, erosive esophagitis, Barrett esophagus, prevention …
disease (GERD), acid-related disorders, erosive esophagitis, Barrett esophagus, prevention …
Association of proton‐pump inhibitor use with adverse health outcomes: a systematic umbrella review of meta‐analyses of cohort studies and randomised controlled …
SK Veettil, S Sadoyu, EM Bald… - British Journal of …, 2022 - Wiley Online Library
Aims The aim was to perform an umbrella review to summarise the existing evidence on
proton‐pump inhibitor (PPI) use and adverse outcomes and to grade the certainty of …
proton‐pump inhibitor (PPI) use and adverse outcomes and to grade the certainty of …
An update on drug–drug interactions associated with proton pump inhibitors
I Ben Ghezala, M Luu, M Bardou - Expert Opinion on Drug …, 2022 - Taylor & Francis
ABSTRACT Introduction Proton pump inhibitors (PPIs) block the gastric H/K-ATPase,
therefore inhibiting acid gastric secretion, leading to an increased pH (> 4). They account for …
therefore inhibiting acid gastric secretion, leading to an increased pH (> 4). They account for …
Does the long-term administration of proton pump inhibitors increase the risk of adverse cardiovascular outcomes? A ChatGPT powered umbrella review
E Teperikidis, A Boulmpou, V Potoupni, S Kundu… - Acta …, 2023 - Taylor & Francis
Abstract Background Proton pump inhibitors (PPIs) are commonly prescribed for the
treatment of acid-related disorders. In the context of coronary artery disease (CAD), PPIs are …
treatment of acid-related disorders. In the context of coronary artery disease (CAD), PPIs are …
Clinical outcomes of concomitant use of proton pump inhibitors and dual antiplatelet therapy: a systematic review and meta-analysis
H Guo, Z Ye, R Huang - Frontiers in Pharmacology, 2021 - frontiersin.org
Background: The safety and efficacy associated with the use of proton pump inhibitors (PPIs)
by patients with coronary artery disease receiving dual antiplatelet therapy (DAPT) remain …
by patients with coronary artery disease receiving dual antiplatelet therapy (DAPT) remain …
Proton pump inhibitors and risk of liver cancer and mortality in patients with chronic liver disease: a systematic review and meta-analysis
Background Epidemiological studies investigating the use of proton pump inhibitors (PPI) on
the risk of liver cancer and/or mortality among persons with chronic liver disease (CLD) have …
the risk of liver cancer and/or mortality among persons with chronic liver disease (CLD) have …
Updated insights on cardiac and vascular risks of proton pump inhibitors: A real-world pharmacovigilance study
Y Zhai, X Ye, F Hu, J Xu, X Guo, Z Lin… - Frontiers in …, 2022 - frontiersin.org
Background Proton pump inhibitors (PPIs) are among the most widely prescribed
medications in clinical practice. However, there are also concerns about the potential risks of …
medications in clinical practice. However, there are also concerns about the potential risks of …
Optimizing antithrombotic therapy in patients with coexisting cardiovascular and gastrointestinal disease
Balancing the safety and efficacy of antithrombotic agents in patients with gastrointestinal
disorders is challenging because of the potential for interference with the absorption of …
disorders is challenging because of the potential for interference with the absorption of …