The motor signs of Parkinson's disease are thought to result in large part from a reduction of
the level of dopamine in the basal ganglia. Over the last few years, many of the functional …

The mesolimbic dopaminergic (ML-DA) system has been recognized for its central role in
motivated behaviors, various types of reward, and, more recently, in cognitive processes …

In patients with Parkinson's disease and in animal models of this disorder, neurons in the
basal ganglia and related regions in thalamus and cortex show changes that can be …

Neurons in the basal ganglia output nuclei display rhythmic burst firing after chronic
nigrostriatal lesions. The thalamocortical network is a strong endogenous generator of …

Our understanding of the pathophysiology of movement disorders and associated changes
in basal ganglia activities has significantly changed during the last few decades. This …

The availability of suitable animal models and the opportunity to record electrophysiologic
data in movement disorder patients undergoing neurosurgical procedures has allowed …

The GABA projection neurons of the substantia nigra pars reticulata (SNr) are output
neurons for the basal ganglia and thus critical for movement control. Their most striking …

Through their repetitive discharge, GABAergic neurons of the substantia nigra pars reticulata
(SNr) tonically inhibit the target nuclei of the basal ganglia and the dopamine neurons of the …

The goal of the present study was to determine the phase relationships of the slow
oscillatory activity that emerges in basal ganglia nuclei in anesthetized rats after dopamine …

Neuronal correlates of Parkinson's disease (PD) include a shift to lower frequencies in the
electroencephalogram (EEG) and enhanced synchronized oscillations at 3–7 and 7–30Hz …