The growing biopharmaceutical industry has reached a level of maturity that allows for the
monitoring of numerous key variables for both process characterization and outcome …

Biotechnological processes are essential for developing economies that aim to stand out in
future markets. The use of bioreactors is one of the most important unit operations of …

Achieving large-scale, cost-effective, and reproducible manufacturing of stem cells with the
existing devices is challenging. Traditional single-use cell-bag bioreactors, limited by their …

Advanced control strategies are well established in chemical, pharmaceutical, and food
processing industries. Over the past decade, the application of these strategies is being …

The high population growth rate, massive animal food consumption, fast economic progress,
and limited food resources could lead to a food crisis in the future. There is a huge …

In this study, three-dimensional flow measurements by means of 4D-Particle Tracking
Velocimetry (4D-PTV) are carried out in a laboratory-scale 3 L stirred tank reactor in order to …

Cells often communicate by the secretion, transport, and perception of molecules.
Information conveyed by molecules is encoded, transmitted, and decoded by cells within the …

Abstract This study employs Lagrangian Sensor Particles (LSPs) with a diameter of 40 mm
equipped with a pressure sensor to investigate cell lifelines in a 15,000 L stirred tank reactor …

Harnessing the potential of biocatalytic conversion of renewable biomass into value-added
products is still hampered by unfavorable process economics. This has promoted the use of …

The galvanic dissolved oxygen sensor finds widespread applications in multiple critical
fields due to its high precision and excellent stability. As its core sensing components, the …