The immune and skeletal systems share a variety of molecules, including cytokines,
chemokines, hormones, receptors, and transcription factors. Bone cells interact with immune …

The bone is an essential organ for locomotion and protection of the body, as well as
hematopoiesis and mineral homeostasis. In order to exert these functions throughout life …

Established RAW264. 7 cell lines for osteoclastic differentiation has been widely engaged in
bone homeostasis research, however, the efficacy of RANKL independently stimulating has …

Osteoclasts are myeloid lineage-derived bone-resorbing cells of hematopoietic origin. They
differentiate from myeloid precursors through a complex regulation process where the …

Cerebrospinal fluid (CSF) is a body fluid of choice for biomarker studies of brain disorders
but remains relatively under-studied compared with other biological fluids such as plasma …

Calcium (Ca2+) plays an important role in regulating the differentiation and function of
osteoclasts. Calcium oscillations (Ca oscillations) are well-known phenomena in receptor …

It has been reported that taxifolin inhibit osteoclastogenesis in RAW264. 7 cells. In our
research, the inhibition effects of taxifolin on the osteoclastogenesis of human bone marrow …

Dynamic regulation of the mitochondrial network by mitofusins (MFNs) modulates energy
production, cell survival, and many intracellular signaling events, including calcium …

The development of patient-derived tumor organoids (TOs) from an epithelial ovarian cancer
tumor obtained at the time of primary or interval debulking surgery has the potential to play …

To counter HIV latency, it is important to develop a better understanding of the full range of
host factors promoting latency. Their identification could suggest new strategies to reactivate …