The worldwide development of antimicrobial resistance forces scientists to search for new
compounds to which microbes would be sensitive. Many new structures contain the 1, 3, 4 …

The quinoline scaffolds are privileged for their numerous biological activities in the
pharmaceutical field. This moiety constitutes a well‐known space in several marketed …

Abstract New fifteen 7-chloroquinolines (M1a-o) were synthesized by microwave irradiation
and conventional route via Schiff-base reaction. The key intermediate 4-((7-chloroquinolin-4 …

A series of benzoquinoline-employing heterocycles was synthesized by treating 3-
chlorobenzo [f] quinoline-2-carbaldehyde with N-phenyl-3-methylpyrazolone, 4 …

Drug discovery is the process through which potential new therapeutic entities are identified,
using a combination of computational, experimental, translational, and clinical models (see …

DNA gyrase and topoisomerase IV (topo IV) inhibitors are among the most interesting
antibacterial drug classes without antibacterial pipeline representative. Twenty-four new …

1, 3, 4-Oxadiazole, a five-membered aromatic ring can be seen in a number of synthetic
molecules. The peculiar structural feature of 1, 3, 4-oxadiazole ring with pyridine type of …

Novel Schiff's base hydrazone derivatives (1–24) based on polyhydroquinoline (PHQ) were
synthesized in good to excellent yields via three step reactions. Compound 1 (starting …

Malaria has been a major parasitic disease in tropical and subtropical regions and is
estimated to kill between one and two million people (mainly children) every year. Novel anti …

Background: This review elaborates the updated synthetic and pharmacological approaches
of a known group of dihydropyrimidinones/thiones from the multi-component reaction like …