Hypertrophic scarring: the greatest unmet challenge after burn injury

CC Finnerty, MG Jeschke, LK Branski, JP Barret… - The Lancet, 2016 - thelancet.com
Improvements in acute burn care have enabled patients to survive massive burns that would
have once been fatal. Now up to 70% of patients develop hypertrophic scars after burns. The …

Overview of silk fibroin use in wound dressings

M Farokhi, F Mottaghitalab, Y Fatahi… - Trends in …, 2018 - cell.com
Recently, biomimetic wound dressings were introduced as potential replacements for
treating skin injuries. Although there are some clinically available skin replacements, the …

Regeneration of dermis: scarring and cells involved

AL Rippa, EP Kalabusheva, EA Vorotelyak - Cells, 2019 - mdpi.com
There are many studies on certain skin cell specifications and their contribution to wound
healing. In this review, we provide an overview of dermal cell heterogeneity and their …

Skin tissue regeneration for burn injury

A Shpichka, D Butnaru, EA Bezrukov… - Stem cell research & …, 2019 - Springer
The skin is the largest organ of the body, which meets the environment most directly. Thus,
the skin is vulnerable to various damages, particularly burn injury. Skin wound healing is a …

Regenerative scar-free skin wound healing

M Monavarian, S Kader, S Moeinzadeh… - … Engineering Part B …, 2019 - liebertpub.com
Scar formation is a common consequence of skin injuries that lead to a wide range of
adverse effects including physical deformities and psychological disorders. Studies …

Clinical applications of acellular dermal matrices: a review

K Petrie, CT Cox, BC Becker… - Scars, Burns & …, 2022 - journals.sagepub.com
Introduction The extracellular matrix (ECM) plays an integral role in wound healing. It
provides both structure and growth factors that allow for the organised cell proliferation …

Skin tissue engineering advances in severe burns: review and therapeutic applications

AWC Chua, YC Khoo, BK Tan, KC Tan, CL Foo… - Burns & …, 2016 - academic.oup.com
Current advances in basic stem cell research and tissue engineering augur well for the
development of improved cultured skin tissue substitutes: a class of products that is still …

Recent advances on biomedical applications of scaffolds in wound healing and dermal tissue engineering

A Rahmani Del Bakhshayesh, N Annabi… - Artificial cells …, 2018 - Taylor & Francis
The tissue engineering field has developed in response to the shortcomings related to the
replacement of the tissues lost to disease or trauma: donor tissue rejection, chronic …

Recent trends in decellularized extracellular matrix bioinks for 3D printing: an updated review

K Dzobo, KSCM Motaung, A Adesida - International journal of molecular …, 2019 - mdpi.com
The promise of regenerative medicine and tissue engineering is founded on the ability to
regenerate diseased or damaged tissues and organs into functional tissues and organs or …

A review of tissue-engineered skin bioconstructs available for skin reconstruction

RV Shevchenko, SL James… - Journal of the royal …, 2010 - royalsocietypublishing.org
Situations where normal autografts cannot be used to replace damaged skin often lead to a
greater risk of mortality, prolonged hospital stay and increased expenditure for the National …