[HTML][HTML] A comprehensive overview of graph neural network-based approaches to clustering for spatial transcriptomics T. Liu et al. Overview of Spatial Transcriptomics …

T Liu, ZY Fang, Z Zhang, Y Yu, M Li, MZ Yin - Computational and Structural …, 2023 - Elsevier
Spatial transcriptomics technologies enable researchers to accurately quantify and localize
messenger ribonucleic acid (mRNA) transcripts at a high resolution while preserving their …

Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues

D Pham, X Tan, B Balderson, J Xu, LF Grice… - Nature …, 2023 - nature.com
Spatial transcriptomics (ST) technologies generate multiple data types from biological
samples, namely gene expression, physical distance between data points, and/or tissue …

BANKSY unifies cell typing and tissue domain segmentation for scalable spatial omics data analysis

V Singhal, N Chou, J Lee, Y Yue, J Liu, WK Chock… - Nature Genetics, 2024 - nature.com
Spatial omics data are clustered to define both cell types and tissue domains. We present
Building Aggregates with a Neighborhood Kernel and Spatial Yardstick (BANKSY), an …

Spatial multi-omics: novel tools to study the complexity of cardiovascular diseases

P Kiessling, C Kuppe - Genome Medicine, 2024 - Springer
Spatial multi-omic studies have emerged as a promising approach to comprehensively
analyze cells in tissues, enabling the joint analysis of multiple data modalities like …

Benchmarking spatial clustering methods with spatially resolved transcriptomics data

Z Yuan, F Zhao, S Lin, Y Zhao, J Yao, Y Cui… - Nature …, 2024 - nature.com
Spatial clustering, which shares an analogy with single-cell clustering, has expanded the
scope of tissue physiology studies from cell-centroid to structure-centroid with spatially …

Stgnnks: identifying cell types in spatial transcriptomics data based on graph neural network, denoising auto-encoder, and k-sums clustering

L Peng, X He, X Peng, Z Li, L Zhang - Computers in Biology and Medicine, 2023 - Elsevier
Background: Spatial transcriptomics technologies fully utilize spatial location information,
tissue morphological features, and transcriptional profiles. Integrating these data can greatly …

Spatial-linked alignment tool (SLAT) for aligning heterogenous slices

CR Xia, ZJ Cao, XM Tu, G Gao - Nature Communications, 2023 - nature.com
Spatially resolved omics technologies reveal the spatial organization of cells in various
biological systems. Here we propose SLAT (Spatially-Linked Alignment Tool), a graph …

Identifying spatial domains of spatially resolved transcriptomics via multi-view graph convolutional networks

X Shi, J Zhu, Y Long, C Liang - Briefings in Bioinformatics, 2023 - academic.oup.com
Motivation: Recent advances in spatially resolved transcriptomics (ST) technologies enable
the measurement of gene expression profiles while preserving cellular spatial context …

SPIRAL: integrating and aligning spatially resolved transcriptomics data across different experiments, conditions, and technologies

T Guo, Z Yuan, Y Pan, J Wang, F Chen, MQ Zhang, X Li - Genome Biology, 2023 - Springer
Properly integrating spatially resolved transcriptomics (SRT) generated from different
batches into a unified gene-spatial coordinate system could enable the construction of a …

Spatial-MGCN: a novel multi-view graph convolutional network for identifying spatial domains with attention mechanism

B Wang, J Luo, Y Liu, W Shi, Z Xiong… - Briefings in …, 2023 - academic.oup.com
Motivation Recent advances in spatial transcriptomics technologies have enabled gene
expression profiles while preserving spatial context. Accurately identifying spatial domains is …