[PDF][PDF] Liver macrophages: old dogmas and new insights

A Guillot, F Tacke - Hepatology communications, 2019 - Wiley Online Library
Inflammation is a hallmark of virtually all liver diseases, such as liver cancer, fibrosis,
nonalcoholic steatohepatitis, alcoholic liver disease, and cholangiopathies. Liver …

[HTML][HTML] Resolving inflammation by TAM receptor activation

JP Vago, FA Amaral, FAJ van de Loo - Pharmacology & Therapeutics, 2021 - Elsevier
The control of inflammation is strictly regulated to ensure the adequate intensity and duration
of an inflammatory response, enabling the removal of the trigger factors and the restoration …

Single-cell RNA transcriptome landscape of hepatocytes and non-parenchymal cells in healthy and NAFLD mouse liver

Q Su, SY Kim, F Adewale, Y Zhou, C Aldler, M Ni… - Iscience, 2021 - cell.com
Nonalcoholic fatty liver disease (NAFLD) is a global health-care problem with limited
therapeutic options. To obtain a cellular resolution of pathogenesis, 82,168 single-cell …

Vitamin D3 as potential treatment adjuncts for COVID-19

L Malaguarnera - Nutrients, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus type (SARS-CoV2, also known as COVID-
19), which is the latest pandemic infectious disease, constitutes a serious risk to human …

Adaptive innate immunity or innate adaptive immunity?

J Černý, I Stříž - Clinical science, 2019 - portlandpress.com
The innate immunity is frequently accepted as a first line of relatively primitive defense
interfering with the pathogen invasion until the mechanisms of 'privileged'adaptive immunity …

B10 cells regulate macrophage polarization to alleviate inflammation and bone loss in periodontitis

G Cao, Q Xu, S Huang, D Dai, J Wang… - Journal of …, 2024 - Wiley Online Library
Background The polarization of macrophages into an anti‐inflammatory phenotype is crucial
for resolving periodontal inflammation. It has been reported that B10 cells can regulate the …

Eschar dissolution and the immunoregulator effect of keratinase on burn wounds

Y Xu, K Hu, C Liu, P Du, F Zhou, Y Lu, Q Fu, J Xu… - Scientific Reports, 2023 - nature.com
At present, enzyme debridement preparation has shown a good curative effect on eschar
removal of burn wounds. Keratinase has shown great potential in enzymatic debridement …

The tumour immune landscape and its implications in cutaneous melanoma

GH Attrill, PM Ferguson, U Palendira… - Pigment Cell & …, 2021 - Wiley Online Library
The field of tumour immunology has rapidly advanced in the last decade, leading to the
advent of effective immunotherapies for patients with advanced cancers. This highlights the …

Deletion of Insulin-like growth factor II mRNA-binding protein 3 participates in the pathogenesis of recurrent spontaneous abortion by inhibiting IL-10 secretion and …

Y Zhang, F Dai, D Yang, Y Zheng, R Zhu, M Wu… - International …, 2023 - Elsevier
Insulin-like growth factor II mRNA-binding protein 3 (IGF2BP3) has been proved to affect
trophoblast function and embryonic development, but its role and potential mechanism in …

[HTML][HTML] Glucocorticoid-induced leucine zipper modulates macrophage polarization and apoptotic cell clearance

JP Vago, I Galvão, GL Negreiros-Lima… - Pharmacological …, 2020 - Elsevier
Macrophages are professional phagocytes that display remarkable plasticity, with a range of
phenotypes that can be broadly characterized by the M1/M2 dichotomy. Glucocorticoid (GC) …