Owing to recent advances in mass spectrometry (MS), tens to hundreds of proteins, lipids,
and small molecules can be measured in single cells. The ability to characterize the …

Due to the improvements in detection sensitivity, inductively coupled plasma-mass
spectrometry (ICP-MS) has matured to be an exceptional tool for the elemental analysis of …

Element constitution and distribution in tissues and body fluids have increasingly become
key pieces of information in life sciences and medicine, and trace elements may be …

This tutorial review article is highlighting the fundamentals, instrumentation, and most recent
trends of single-cell analysis by use of inductively coupled plasma-mass spectrometry (ICP …

We report the capabilities of an inductively coupled plasma time-of-flight mass spectrometry
(ICP-TOFMS) instrument for single-droplet and single-particle analysis. The icpTOF-S2 …

life science, clinical diagnostics, drug development, etc. Recent years have witnessed the
emergence of innovative analytical methods with high sensitivity and spatial-temporal …

The content, migration and transformation of trace elements in living organisms play an
important role in physiological activities. The analysis of trace elements in cells is of great …

Known as highly efficient metallodrugs that have been clinically used to treat various types
of cancers, cisplatin and its analogues have attracted and inspired extensive interest in the …

The heterogeneity properties shown by cells or unicellular organisms have led to the
development of analytical methods at the single-cell level. In this sense, considering the …

Laser ablation–inductively coupled plasma–mass spectrometry (LA–ICP–MS) is an
emerging method for the analysis of metal nanoparticles (NPs) in single cells. However, two …