The intersection of obesity and (long) COVID-19: Hypoxia, thrombotic inflammation, and vascular endothelial injury

M Xiang, X Wu, H Jing, VA Novakovic… - Frontiers in cardiovascular …, 2023 - frontiersin.org
The role of hypoxia, vascular endothelial injury, and thrombotic inflammation in worsening
COVID-19 symptoms has been generally recognized. Damaged vascular endothelium plays …

Coagulopathy and fibrinolytic pathophysiology in COVID-19 and SARS-CoV-2 vaccination

S Yamada, H Asakura - International Journal of Molecular Sciences, 2022 - mdpi.com
Coronavirus Disease 2019 (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and is frequently complicated by thrombosis. In some cases of …

Arterial and venous thrombosis complicated in COVID-19: a retrospective single center analysis in Japan

S Oba, T Hosoya, M Amamiya, T Mitsumura… - Frontiers in …, 2021 - frontiersin.org
Background: Thrombosis is a characteristic complication in coronavirus disease 2019
(COVID-19). Since coagulopathy has been observed over the entire clinical course …

[HTML][HTML] The current status of thrombosis and anticoagulation therapy in patients with COVID-19 in Japan: From the CLOT-COVID study

Y Nishimoto, S Yachi, M Takeyama, I Tsujino… - Journal of …, 2022 - Elsevier
Background Data on thrombosis and current real-world management strategies for
anticoagulation therapy are scarce but important for understanding current issues and …

Incidence, risk factors, and clinical impact of major bleeding in hospitalized patients with COVID-19: a sub-analysis of the CLOT-COVID Study

J Nakamura, I Tsujino, S Yachi, M Takeyama… - Thrombosis journal, 2022 - Springer
Background The coronavirus disease 2019 (COVID-19) causes extensive coagulopathy and
a potential benefit of anticoagulation therapy has been documented for prevention of …

Influence of sex on development of thrombosis in patients with COVID-19: From the CLOT-COVID study

Y Yamashita, S Yachi, M Takeyama, Y Nishimoto… - Thrombosis research, 2022 - Elsevier
Introduction There has been limited data on the influence of sex on development of
thrombosis in patients with coronavirus disease 2019 (COVID-19). Materials and methods …

Influence of obesity on incidence of thrombosis and disease severity in patients with COVID-19: From the CLOT-COVID study

Y Ogihara, S Yachi, M Takeyama, Y Nishimoto… - Journal of …, 2023 - Elsevier
Background The influence of obesity on the development of thrombosis and severity of
coronavirus disease 2019 (COVID-19) remains unclear. Method The CLOT-COVID study …

Real-world management of pharmacological thromboprophylactic strategies for COVID-19 patients in Japan: from the CLOT-COVID study

H Hayashi, Y Izumiya, D Fukuda, F Wakita, Y Mizobata… - JACC: Asia, 2022 - jacc.org
Background Data on prophylactic anticoagulation are important in understanding the current
issues, unmet needs, and optimal management of Japanese COVID-19 patients. Objectives …

Mortality-associated risk factors in hospitalized COVID-19 patients in Japan: Findings of the CLOT-COVID study

M Takeyama, S Yachi, Y Nishimoto, I Tsujino… - Journal of …, 2023 - jstage.jst.go.jp
Background: Reports of mortality-associated risk factors in patients with the novel
coronavirus disease 2019 (COVID-19) are limited. Methods: We evaluated the clinical …

Urokinase-type plasminogen activator and plasminogen activator inhibitor-1 complex as a serum biomarker for COVID-19

T Yatsenko, R Rios, T Nogueira, Y Salama… - Frontiers in …, 2024 - frontiersin.org
Patients with coronavirus disease-2019 (COVID-19) have an increased risk of thrombosis
and acute respiratory distress syndrome (ARDS). Thrombosis is often attributed to increases …