Metal-catalyzed C–H functionalization involving isocyanides

B Song, B Xu - Chemical Society Reviews, 2017 - pubs.rsc.org
Isocyanides have a broad range of applications in multicomponent reactions such as
Passerini and Ugi processes. Recent advances in metal catalysis have tremendously …

Recent advances in the synthesis of indoles from alkynes and nitrogen sources

JSS Neto, G Zeni - Organic Chemistry Frontiers, 2020 - pubs.rsc.org
Transition metal-catalyzed cyclization reactions of unsaturated substrates have become one
of the most important and useful methodologies for the preparation of heterocycles. To this …

Synthesis of Diversely Functionalized Oxindoles Enabled by Migratory Insertion of Isocyanide to a Transient σ‐Alkylpalladium (II) Complex

W Kong, Q Wang, J Zhu - Angewandte Chemie, 2016 - Wiley Online Library
Palladium‐catalyzed intramolecular carbopalladation of N‐aryl acrylamides followed by
migratory insertion of an isocyanide‐coordinated C (sp3)− Pd intermediate afforded an …

Recent advances in palladium-catalyzed isocyanide insertions

JW Collet, TR Roose, B Weijers, BUW Maes, E Ruijter… - Molecules, 2020 - mdpi.com
Isocyanides have long been known as versatile chemical reagents in organic synthesis.
Their ambivalent nature also allows them to function as a CO-substitute in palladium …

Direct Synthesis of 2-Methylbenzofurans from Calcium Carbide and Salicylaldehyde p-Tosylhydrazones

R Fu, Z Li - Organic letters, 2018 - ACS Publications
A new methodology for the construction of methyl-substituted benzofuran rings from the
reactions of calcium carbide with salicylaldehyde p-tosylhydrazones/2 …

Advances in palladium‐catalyzed cascade cyclizations

J Biemolt, E Ruijter - Advanced Synthesis & Catalysis, 2018 - Wiley Online Library
The past decades in organic chemistry have witnessed significant improvements in synthetic
efficiency as a result of considerable progress in cascade reactions, tandem reactions, and …

Ketenimines from Isocyanides and Allyl Carbonates: Palladium‐Catalyzed Synthesis of β, γ‐Unsaturated Amides and Tetrazoles

G Qiu, M Mamboury, Q Wang, J Zhu - Angewandte Chemie, 2016 - Wiley Online Library
The reaction of allyl ethyl carbonates with isocyanides in the presence of a catalytic amount
of Pd (OAc) 2 provided ketenimines through β‐hydride elimination of the allyl …

C(sp2)–H Functionalization of 2H-Indazoles at C3-Position via Palladium(II)-Catalyzed Isocyanide Insertion Strategy Leading to Diverse Heterocycles

S Vidyacharan, A Murugan… - The Journal of Organic …, 2016 - ACS Publications
Herein, we have reported an efficient Pd-catalyzed C–H functionalization of 2 H-indazole at
C3-position via an isocyanide insertion strategy for the synthesis of unprecedented …

Enantioselective synthesis of planar chiral pyridoferrocenes via palladium-catalyzed imidoylative cyclization reactions

S Luo, Z Xiong, Y Lu, Q Zhu - Organic letters, 2018 - ACS Publications
A highly efficient synthesis of planar chiral pyrido [3, 4-b] ferrocenes by a palladium-
catalyzed enantioselective isocyanide insertion/desymmetric C (sp2)–H bond activation …

Palladium-catalyzed three-component reaction of propargyl carbonates, isocyanides, and alcohols or water: switchable synthesis of pyrroles and its bicyclic …

G Qiu, Q Wang, J Zhu - Organic letters, 2017 - ACS Publications
In the presence of a catalytic amount of Pd (OAc) 2 and a stoichiometric amount of tert-
butylamine, the reaction of propargyl carbonates, isocyanides, and alcohols afforded …