Epidemiology, pathogenesis, diagnosis and emerging treatment of nonalcoholic fatty liver disease

E Makri, A Goulas, SA Polyzos - Archives of medical research, 2021 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, with an
estimated rising prevalence, in concert with the epidemics of obesity and type 2 diabetes …

Lean NAFLD: an underrecognized and challenging disorder in medicine

S Maier, A Wieland, M Cree-Green, K Nadeau… - Reviews in Endocrine …, 2021 - Springer
Abstract Classically, Non-Alcoholic Fatty Liver Disease (NAFLD) has been thought to be
driven by excessive weight gain and obesity. The overall greater awareness of this disorder …

The Asian Pacific Association for the Study of the Liver clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease

M Eslam, SK Sarin, VWS Wong, JG Fan… - Hepatology …, 2020 - Springer
Metabolic associated fatty liver disease (MAFLD) is the principal worldwide cause of liver
disease and affects nearly a quarter of the global population. The objective of this work was …

Noninvasive fibrosis tools in NAFLD: validation of APRI, BARD, FIB-4, NAFLD fibrosis score, and Hepamet fibrosis score in a Portuguese population

J Rigor, A Diegues, J Presa, P Barata… - Postgraduate …, 2022 - Taylor & Francis
Objectives The burden of nonalcoholic fatty liver disease (NAFLD) is increasing, with an
estimated prevalence in Europe of 20–30%. Although most patients present with simple …

Nonalcoholic fatty liver disease: current global burden

M El-Kassas, J Cabezas, PI Coz… - Seminars in liver …, 2022 - thieme-connect.com
The map and global disease burden of chronic liver diseases are markedly changing, with
nonalcoholic fatty liver disease (NAFLD) becoming the most common cause of liver …

Accuracy of Fibrosis-4 index and non-alcoholic fatty liver disease fibrosis scores in metabolic (dysfunction) associated fatty liver disease according to body mass index …

F Eren, E Kaya, Y Yilmaz - European journal of gastroenterology & …, 2022 - journals.lww.com
Methods A total of 560 patients (28 lean, 174 overweight, 229 obese, 89 severely obese, 40
morbidly obese) were included. Diagnostic performances and optimal cut-off values for FIB …

Liver fibrosis scores and prognosis in patients with cardiovascular diseases: a systematic review and meta‐analysis

Z Yan, Y Liu, W Li, X Zhao, W Lin… - European Journal of …, 2022 - Wiley Online Library
Background In patients with nonalcoholic fatty liver disease, liver fibrosis was associated
with a higher risk of cardiovascular events. However, the relationship between liver fibrosis …

The egyptian clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease

Y Fouad, G Esmat, R Elwakil, S Zakaria… - Saudi Journal of …, 2022 - journals.lww.com
The landscape of chronic liver disease in Egypt has drastically changed over the past few
decades. The prevalence of metabolic-associated fatty liver disease (MAFLD) has risen to …

Liver fibrosis is associated with carotid atherosclerosis in patients with liver biopsy-proven nonalcoholic fatty liver disease

T Arai, M Atsukawa, A Tsubota, K Kato, H Abe… - Scientific Reports, 2021 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is related to subclinical atherosclerosis. However,
whether the severity of the disease (or which histopathological component) is associated …

Brazilian evidence-based guideline for screening, diagnosis, treatment, and follow-up of metabolic dysfunction-associated steatotic liver disease (MASLD) in adult …

RO Moreira, CM Valerio… - … of Endocrinology and …, 2023 - SciELO Brasil
Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD), previously
known as Nonalcoholic fatty liver disease (NAFLD), is one of the most common hepatic …