Leptin and ghrelin are two hormones that have been recognized to have a major influence
on energy balance. Leptin is a mediator of long‐term regulation of energy balance …

This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

Obesity is an important cause of morbidity and mortality in developed countries, and is also
becoming increasingly prevalent in the developing world. Although environmental factors …

The last few years have seen major advances in common non-syndromic obesity research,
much of it the result of genetic studies. This Review outlines the competing hypotheses …

It has long been known that there is a genetic component to obesity, and that characterizing
this underlying factor would likely offer the possibility of better intervention in the future …

With the growing prevalence of obesity, scientific interest in the biology of adipose tissue has
been extended to the secretory products of adipocytes, since they are increasingly shown to …

Loos RJF, Bouchard C (Human Genomics Laboratory, Pennington Biomedical Research
Center, Baton Rouge, LA, USA). Obesity–is it a genetic disorder?(Review). J Intern Med …

Cardiovascular disease (CV) is the most common cause of premature mortality in patients
with rheumatoid arthritis (RA). This is the result of an accelerated atherosclerotic process …

This is the tenth update of the human obesity gene map, incorporating published results up
to the end of October 2003 and continuing the previous format. Evidence from single‐gene …

This paper presents the eleventh update of the human obesity gene map, which
incorporates published results up to the end of October 2004. Evidence from single‐gene …