[HTML][HTML] Gut microbiota-derived short-chain fatty acids regulate gastrointestinal tumor immunity: a novel therapeutic strategy?

Y Dong, K Zhang, J Wei, Y Ding, X Wang… - Frontiers in …, 2023 - frontiersin.org
Tumor immune microenvironment (TIME), a tumor-derived immune component, is proven to
be closely related to the development, metastasis, and recurrence of tumors. Gut microbiota …

Microbial metabolites in colorectal tumorigenesis and cancer therapy

Y Liu, HCH Lau, J Yu - Gut Microbes, 2023 - Taylor & Francis
Trillions of microbes are indigenous to the human gastrointestinal tract, together forming an
ecological community known as the gut microbiota. The gut microbiota is involved in dietary …

[HTML][HTML] Microbiota composition and its impact on DNA methylation in colorectal cancer

M Gutierrez-Angulo, ML Ayala-Madrigal… - Frontiers in …, 2023 - frontiersin.org
Colorectal cancer is a complex disease resulting from the interaction of genetics,
epigenetics, and environmental factors. DNA methylation is frequently found in tumor …

[HTML][HTML] Anticancer effects of gut microbiota-derived short-chain fatty acids in cancers

MY Son, HS Cho - Journal of Microbiology and Biotechnology, 2023 - ncbi.nlm.nih.gov
Short-chain fatty acids (SCFAs), such as butyrate, propionate, and acetate produced by the
gut microbiota have been implicated in physiological responses (defense mechanisms …

Histone modification: biomarkers and potential therapies in colorectal cancer

X An, X Lan, Z Feng, X Li, Q Su - Annals of Human Genetics, 2023 - Wiley Online Library
The complex mechanism of colorectal cancer development is closely associated with
epigenetic modifications and is caused by overexpression and/or inactivation of oncogenes …

[HTML][HTML] Antioxidant and anti-inflammatory properties of walnut constituents: Focus on personalized cancer prevention and the microbiome

N Fan, JL Fusco, DW Rosenberg - Antioxidants, 2023 - mdpi.com
Walnuts have been lauded as a 'superfood', containing a remarkable array of natural
constituents that may have additive and/or synergistic properties that contribute to reduced …

Butyrate enhances erastin‐induced ferroptosis of lung cancer cells via modulating the ATF3/SLC7A11 pathway

R Bi, R Hu, L Jiang, B Wen, Z Jiang… - Environmental …, 2024 - Wiley Online Library
Ferroptosis is a novel form of programmed cell death triggered by iron‐dependent lipid
peroxidation and has been associated with various diseases, including cancer. Erastin, an …

[HTML][HTML] Nutraceuticals as potential therapeutic modulators in immunometabolism

G Alba, H Dakhaoui, C Santa-Maria, F Palomares… - Nutrients, 2023 - mdpi.com
Nutraceuticals act as cellular and functional modulators, contributing to the homeostasis of
physiological processes. In an inflammatory microenvironment, these functional foods can …

[HTML][HTML] Genome-wide acetylation modification of H3K27ac in bovine rumen cell following butyrate exposure

X Kang, C Li, S Liu, RL Baldwin, GE Liu, CJ Li - Biomolecules, 2023 - mdpi.com
Butyrate contributes epigenetically to the changes in cellular function and tissue
development of the rumen in ruminant animals, which might be achieved by its genetic or …

[HTML][HTML] Control of redox homeostasis by short-chain fatty acids: implications for the prevention and treatment of breast cancer

C González-Bosch, PA Zunszain, GE Mann - Pathogens, 2023 - mdpi.com
Breast cancer is the leading cause of death among women worldwide, and certain subtypes
are highly aggressive and drug resistant. As oxidative stress is linked to the onset and …