Parkinson's disease (PD) is a complex, multisystem disorder with both neurologic and
systemic manifestations, which is usually associated with non-motor symptoms, including …

Purpose Different dietary supplements aimed at improving sleep quality are available on the
market, but there has not been a comprehensive review to evaluate the efficacy of these …

Purpose The trial aimed to investigate the effectiveness of exogenous melatonin as an
adjuvant to pregabalin for relief of pain in patients suffering from painful diabetic neuropathy …

Previous systematic reviews and meta-analyses of randomized controlled trials have
reported controversial findings regarding the effects of melatonin on pain reduction. The aim …

Chemotherapy‐induced peripheral neuropathy (CIPN) frequently occurs in cancer patients.
This side effect lowers the quality of life of patients and may cause the patients to abandon …

Soluble epoxide hydrolase (sEH) is related to arachidonic acid cascade and is over-
expressed in a variety of diseases, making sEH an attractive target for the treatment of pain …

2. Methods This study was conducted as a systematic review and reported according to the
Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement …

Cannabis sativa L.(hemp) is a herbaceous plant rich in cannabinoids with a long history of
use in pain treatment. The most well-characterized cannabinoids, cannabidiol (CBD) and Δ9 …

Gabapentin, as an anticonvulsant drug with its low-permeability feature in the
gastrointestinal region, is one of the commonly prescribed medications for the treatment of …

神经病理性疼痛(neuropathic pain, NP) 是一直困扰人类的医学难题, 严重影响人民生活质量.
尽管近年来关于NP 的研究取得了很大进展, 但是依旧有很多患者对现有的治疗无效 …