[HTML][HTML] Utility of cockroach as a model organism in the assessment of toxicological impacts of environmental pollutants

IA Adedara, KA Mohammed, OF Da-Silva… - Environmental …, 2022 - Elsevier
Environmental pollution is a global concern because of its associated risks to human health
and ecosystem. The bio-monitoring of environmental health has attracted much attention in …

Dietary inclusions of Solanum vegetables mitigate aluminum-induced redox and inflammation-related neurotoxicity in Drosophila melanogaster model

OB Ogunsuyi, OC Olagoke, BA Afolabi… - Nutritional …, 2022 - Taylor & Francis
Background This study investigated the modulatory capacity of two Solanum green leafy
vegetables; S. macrocarpon L.(African eggplant AE) and S. nigrum L.(Black nightshade BN) …

Isoformononetin, a dietary isoflavone protects against streptozotocin induced rat model of neuroinflammation through inhibition of NLRP3/ASC/IL-1 axis activation

S Chaturvedi, V Tiwari, NM Gangadhar, M Rashid… - Life Sciences, 2021 - Elsevier
Aims Isoformononetin (IFN), a methoxyl isoflavone present in most of human dietary
supplements. However, being a highly potent antioxidant and anti-inflammatory molecule, its …

Neurobehavioral, neurotransmitter and redox modifications in Nauphoeta cinerea under mixed heavy metal (silver and mercury) exposure

OC Olagoke, OB Ogunsuyi, FE Mayokun… - BMC Research …, 2024 - Springer
Heavy metals are encountered in nature, and are used in several human endeavors,
including in dental fillings. It is well known that the safety of metals depends on their …

Effect of Solanum vegetables on memory index, redox status, and expressions of critical neural genes in Drosophila melanogaster model of memory impairment

OB Ogunsuyi, OC Olagoke, BA Afolabi, JS Loreto… - Metabolic brain …, 2022 - Springer
African eggplant (Solanum macrocarpon L)(AE) and Black Nightshade (Solanum nigrum
L)(BN) leaves are green leafy vegetables with nutritional and ethnobotanical values. We …

Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems

OB Ogunsuyi, OP Aro, G Oboh… - Drug and Chemical …, 2023 - Taylor & Francis
One of the well-established models for examining neurodegeneration and neurotoxicity is
the Drosophila melanogaster model of aluminum-induced toxicity. Anti-cholinesterase drugs …

JNK‐ and Rel‐Mediated Regulation of Inflammation and Neurotoxicity in Nauphoeta cinerea Exposed to Methylmercury and Monosodium Glutamate

BA Obafemi, IA Adedara, ALA Segatto… - Journal of Food …, 2023 - Wiley Online Library
Food contaminants are closely monitored to establish food safety profiles. Previously, we
used the lobster cockroach to delineate the oxidative and antioxidant activities that …

Administration of curcumin plus treadmill exercise modulate some neuronal enzyme activities, redox markers and BDNF mRNA expression in pilocarpine-induced …

OB Ogunsuyi, PO Aro, HI Umar, G Oboh - Neurochemical Journal, 2023 - Springer
Epilepsy, a chronic neurological illness, takes a heavy emotional toll on patients and their
families. It is one of most neglected neurological illnesses in Africa. Studies have shown that …

Neural acetylcholinesterase and monoamine oxidase deregulation during streptozotocin-induced behavioral, metabolic and redox modification in Nauphoeta cinerea

OB Ogunsuyi, OC Olagoke, ME Famutimi… - BMC neuroscience, 2024 - Springer
Genetic and environmental factors have been linked with neurodegeneration, especially in
the elderly. Yet, efforts to impede neurodegenerative processes have at best addressed …

Bitter gourd flavored Non-Alcoholic Wheat Beer (NAWB) exhibited antidiabetic properties by modulating carbohydrate metabolizing enzymes and upregulates insulin …

GP Akerele, BC Adedayo, G Oboh… - … Processing and Nutrition, 2023 - Springer
To improve the control of Type 2 diabetes (T2D), this study investigated the potential benefits
of an alcohol-free beer flavored with bitter gourd leaves, a plant with proven hypoglycemic …