Antimicrobial peptides from scorpion venoms

PL Harrison, MA Abdel-Rahman, K Miller, PN Strong - Toxicon, 2014 - Elsevier
The need for new antimicrobial agents is becoming one of the most urgent requirements in
modern medicine. The venoms of many different species are rich sources of biologically …

A global accounting of medically significant scorpions: Epidemiology, major toxins, and comparative resources in harmless counterparts

MJ Ward, SA Ellsworth, GS Nystrom - Toxicon, 2018 - Elsevier
Scorpions are an ancient and diverse venomous lineage, with over 2200 currently
recognized species. Only a small fraction of scorpion species are considered harmful to …

Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones)

EF Schwartz, E Diego-Garcia… - BMC genomics, 2007 - Springer
Background Scorpions like other venomous animals posses a highly specialized organ that
produces, secretes and disposes the venom components. In these animals, the last …

Proteomic analysis of the venom from the scorpion Tityus stigmurus: biochemical and physiological comparison with other Tityus species

CVF Batista, SA Román-González… - … and Physiology Part C …, 2007 - Elsevier
The venom from the Brazilian scorpion Tityus stigmurus was fractionated by high
performance liquid chromatography (HPLC) and the corresponding components were used …

Scorpion venom as a source of antimicrobial peptides: overview of biomolecule separation, analysis and characterization methods

S Nasr, A Borges, C Sahyoun, R Nasr, R Roufayel… - Antibiotics, 2023 - mdpi.com
Scorpion venoms have long captivated scientific researchers, primarily due to the potency
and specificity of the mechanism of action of their derived components. Among other …

Extreme diversity of scorpion venom peptides and proteins revealed by transcriptomic analysis: implication for proteome evolution of scorpion venom arsenal

Y Ma, Y He, R Zhao, Y Wu, W Li, Z Cao - Journal of proteomics, 2012 - Elsevier
Venom is an important genetic development crucial to the survival of scorpions for over
400million years. We studied the evolution of the scorpion venom arsenal by means of …

Identification and Phylogenetic Analysis of Tityus pachyurus and Tityus obscurus Novel Putative Na+-Channel Scorpion Toxins

JA Guerrero-Vargas, CBF Mourao… - PLoS …, 2012 - journals.plos.org
Background Colombia and Brazil are affected by severe cases of scorpionism. In Colombia
the most dangerous accidents are caused by Tityus pachyurus that is widely distributed …

Intraspecific variation in the Egyptian scorpion Scorpio maurus palmatus venom collected from different biotopes

MA Abdel-Rahman, MAA Omran, IM Abdel-Nabi… - Toxicon, 2009 - Elsevier
The present study was conducted to explore the following hypotheses:(i) do scorpions
(Scorpio maurus palmatus) from different biotopes exhibit intraspecific diversity in their …

[HTML][HTML] An overview of Tityus cisandinus scorpion venom: Transcriptome and mass fingerprinting reveal conserved toxin homologs across the Amazon region and …

Y Kalapothakis, K Miranda, DAM Molina… - International Journal of …, 2023 - Elsevier
Tityus cisandinus, a neglected medically important scorpion in Ecuadorian and Peruvian
Amazonia, belongs to a complex of species related to the eastern Amazon endemic Tityus …

Venom diversity in the Neotropical scorpion genus Tityus: Implications for antivenom design emerging from molecular and immunochemical analyses across endemic …

A Borges, B Lomonte, Y Angulo, HA de Patiño… - Acta Tropica, 2020 - Elsevier
Scorpions of the Neotropical genus Tityus are responsible for most severe envenomations in
the Caribbean, South America, and Lower Central America (LCA). Although Tityus is …